Disease of salivary glands- malignant

Question 1

List malignant salivary gland tumors:

Answer 1

1. mucoepidermoid carcinoma
2. adenoid cystic carcinoma
3. polymorphous low-grade adenocarcinoma
4. acinic cell carcinoma
5. carcinoma ex-mixed tumor
6. adenocarcinoma NOS

Question 2

-most common malignant salivary gland neoplasm
- middle-aged females
- clinically mistaken for a mucocele

Answer 2

mucoepidermoid carcinoma

Question 3

What malignant salivary gland neoplasm is clinically mistaken for a mucocele?

Answer 3

Mucoepidermoid carcinoma

Question 4

Patient presents with some palatal swelling with some redness and a small point of the start of ulceration. It loos very similar to a mucocele, what is the potential diagnosis?

Answer 4

Mucoepidermoid carcinoma

Question 5

Diagnose what is seen on the lower lip. The patient states that it is painful and you see a small point of ulceration. What is the differential diagnosis for this?

Answer 5

Mucoepidermoid carcinoma

Question 6

We don’t see a lot of malignant salivary gland neoplasms on the lip, but if we do see one, it is most likely:

Answer 6

mucoepidermoid carcinoma

Question 7

What malignant tumor presents histologically with:

• mucous producing cells
• epidermoid (squamous) cells
• may be cystic and/or solid

Answer 7

mucoepidermoid carcinoma

Question 8

Because it is very hard to differentiate between a high grade mucoepidermoid carcinoma and a squamous cell carcinoma, what staining method may be beneficial for diagnosis:

Answer 8

mucicarmine stain

Question 9

• best recognized salivary gland tumor
• middle-aged females
• slow growing mass
• painful
• malignant

Answer 9

Adenoid cystic carcinoma

Question 10

Pt presents with a malignant tumor of the tongue. This is not common, what is the most likely diagnosis?

Answer 10

Adenoid cystic carcinoma

Question 11

What malignant tumor presents histologically with:

-myoepithelial and ductal cells
- perineurial and perivascular invasion (contributes to poor prognosis)
-cribiform pattern
-SWISS CHEESE

Answer 11

Adenoid cystic carcinoma

Question 12

What contributes to the poor prognosis of adenoid cystic carcinoma?

Answer 12

Perineural & perivascular invasion

Question 13

• most common malignant minor salivary gland tumor
• middle-aged females
• favors palate

Answer 13

Polymorphous low-grade adenocarcinoma

Question 14

If we see a tumor of the retromolar pad, it is mostly likely going to be:

Answer 14

malignant (mucoepidermoid carcinoma)

Question 15

What malignant tumor presents histologically with:

• deceptive uniform appearance
• different growth patterns
• perineural and perivascular invasion
• Indian filing

Answer 15

PLGA

Question 16

In this histological image we can see this Indian filing pattern due to perivascular invasion. What is the diagnosis?

Answer 16

PLGA

Question 17

• Parotid gland
• serous acinar differentiation
• middle-aged females
• slow-growing
• low-grade malignancy

Answer 17

acinic cell carcinoma

Question 18

What malignant tumor presents histologically with:

• well circumscribed
• may be infiltrative
• serous acinar cell (abundant granular basophilic cytoplasm and a round, stained ecentric nucleus)

Answer 18

acinic cell carcinoma

Question 19

• long standing pleomorphic adenoma
• older adults
• rapid growth
• pain & ulceration

Answer 19

carcinoma ex-pleomorphic adenoma

Question 20

Your patient initially had the diagnosis of pleomorphic adenoma. They did not get treatment and this condition worsened accompanied by pain and ulceration. Diagnosis?

Answer 20

Carcinoma ex-pleomorphic adenoma

Question 21

What malignant tumor presents histologically with:

• typical benign mixed tumor
• malignant degeneration
• cellular pleomorphism
• abnormal mitotic activity
• capsular invasion

Answer 21

carcinoma ex-pleomorphic adenoma

Question 22

• uncommon salivary gland neoplasm
• cannot be classified
• middle- aged females

Answer 22

adenoma carcinoma NOS