Anemia In Pregnancy

Question 1

Most common cause of anemia in pregnancy ?

Answer 1

Iron difference due to increase in demand

Question 2

Secondary causes of anemia are ?

Answer 2

Sickle cell anemia
Autoimmune hemolytic

Question 3

Main 3 types of anemia in pregnancy

Answer 3

Microplastic -iron decency
Megaloblastic-due to folate and b12
Hemoglobinopathy -sickle cell

Question 4

Anemia in pregnancy defined as

Answer 4

Hb less than 11-first trimester
Hb less than 10.5 -second and third
Hb less Han 10 -postpartum

Question 5

General approach to anemic pregnant ?

Answer 5

-Preconception Hb monitoring
-keep in mind that ida is the most common cause of anemia
- treat he cause
-avoid post partum complication
-give proper contraception methods (progesterone containing )

Question 6

The best contraception for sickle cell crisis ?

Answer 6

Progesterone containing

Question 7

Common complication of anemia in pregnancy

Answer 7

1- decrease placenta weight
2-increase risk of miscarriage
3-increase risk of infertility
4- pulmanory complication
5- bone crisis
6-painful crisis
7- increase risk for cesarean section

Question 8

Megaloblasic anemia ?

Answer 8

Impaired dna synthesis due to non infective erythropoiesis due to b12 and folate deficiency

Question 9

Magaloplastic Progress and occurs at which trimester

Answer 9

Slow and common at 3 trimester

Question 10

Symptoms of megaloblastic anemia ?

Answer 10

Weight loss
Anorexia
Bleeding (due to thrombocytopenia)
Glottises

Question 11

Out comes in pregnancy ?

Answer 11

Preeclampsia
Placental abruption
Iugr
Neural tube defect

Question 12

Labs for megaloblastic anemia

Answer 12

Blood smear
-Howell body
-hypersegmanted neutrophils
—macrocytic normochroic anemia
Erythrocyte folate level

Question 13

Megaloblastic anemia treated by giving

Answer 13

B12 (im) cobalamine 1mg monthly
Flic acid 1 mg /day

Question 14

Adult hemoglobin is made of

Answer 14

Hba1 - 2 alpha Chain and 2 beta chain

Question 15

Thalassemia is

Answer 15

Deficiency in producing hba1 chains
(Deficiency in producing alpha and beta globin due to genetic mutations

Question 16

Thalassemia inheritance type

Answer 16

Autosomal recessive

Question 17

Alpha thalassemia major effect on pregnancy

Answer 17

-incompatible with life
-sever anemia
-hydros fetalis
Polyhydrominus
-abnormal organogenesis

Question 18

Alpha major maternal risk ?

Answer 18

—preeclampsia
—placental abruption
—Gestational hypertension
—aph
—pph

Question 19

Hbh disease ?

Answer 19

It’s when 3 alpha genes are deletes
-splenomegaly
-worsen in pregnancy
-moderate hemolytic anemia

Question 20

Effect of b thalassemia trait ??

Answer 20

Mild anemia

Question 21

Beta major thalassemia ?

Answer 21

Increase risk of blood transfusion
Iugr
Risk of cs
Iron overload
Fetal hypoxia

Question 22

What is the sickle cell anemia ?

Answer 22

Sickle shape rbc due to autosomal recessive mutation

Question 23

Sickle cell is commo in which race ?

Answer 23

Middle East
African American

Question 24

The most commmon phenotype of sickle cell anemia ?

Answer 24

Homogenous (HBSS)

Question 25

The main feature of Hb ss is ?

Answer 25

Less soluble tend to distort rbc

Question 26

Why risk of sickle cell increase in pregnancy ?

Answer 26

Increase metabolic requirements
Hyper coagulable state
Vascular stasis

Question 27

Pathogenisis ?

Answer 27

Hemolytic anemia -extravascular hemolysis -chronic anemia -microvascular obstruction (vaso occlusive crisis

Question 28

Pregnant with sickle cell should be tested frequently foe ?

Answer 28

UTI
Blood pressure

Question 29

Complication of sickle cell ?

Answer 29

Iugr
Iufd
Preeclampsia
Preterm labor
Miscarriage

Question 30

Labs should. Done for sickle cells anemia?

Answer 30

Normocytic normochromic
Increase reticylocte count
Increase ldh
Decrease heptoglobin

Question 31

Sickle cell on blood smear

Answer 31

How’ll jolly body
Target cell
Sickle cell