Exam review Flashcards
Cyclosporin does not suppress the BM and works on IL___ and the main SE is ….
Cyclosporin does not suppress the BM and usually has GI side effects, works on IL-2 and the main SE is GI upset but can also cause gingival hyperplasia
What are some causes for increased bilirubin?
prehepatic- Intravascular (like hemolysis), hepatic (liver failure so unable to break it down), and post hepatic like cholestasis
What enzyme/value of serum chemistry tells you about liver function and NOT damage?
ALP (half life is very long, like weeks to months and can be elevated due to many, many things!!!!)
What enzyme/value on serum chemistry tells you about liver damage but not function?
ALT (half life is 60 hours in dog and 4-6 hours in a cat)
HCM notes to know–
Left atrium dilated because left ventricle gets larger and atria does not handle well with high pressure so it will hypertrophy and when left atrium gets big enough it creates “smoke” signs on echo with turbulent blood flow
What is involved in the breakdown of a blood clot?
FDP’s, uses up antithrombin so that gets decreased, and D-dimers are used
What is directly involved with rat bait toxicity? (I am looking for an enzyme here)
Vitamin K epoxide reductase which is the enzyme that is involved with anti-coagulating with rat bait toxicity
What elevates first with anti coag toxicity?
PT because involves factor 7 which has the shortest half life
Hyperadrenocorticism is usually pituitary dependent or adrenal dependent?
Pituitary dependent
___% of pit tumors are microadenomas (tumor of the pituitary gland in the brain and are less than 1cm) that turn into MACRadenomas
20%
When can you see proteinuria without any other urinalysis abn?
Amyloidosis (think sher peis) and glomerulonephritis (can have normal BUN in these p but WILL HAVE loss of proteins in the urine)
Know all about LLDST and HDDST
..
Normal calcium in animals is __-__ on serum chem and is VERY VERY VERY VERY VERY VERYYY TIGHTLY REGULATED
like 9.4- 11
even 0.1 off is something to dive deeper into….
GSD with weight loss despite normal appetite 6 y/o MN is likely NOT what disease???
hyperadrenocorticism
Primary hyperparathyroidism calcium and phosphorus levels…
high calcium and low phosphorus
What will iron def look like in terms of MCV and MCHC?
Microcytic micro chromic
____ is always artifact on MCHC
Hyperchromic (cannot get more hgb into cells than they already have….)
What will MCV and MCHC look like in terms of NON- regenerative anemia???
Normocytic and normochromic