Cancer Flashcards
cancer
the uncontrolled inappropriate growth of cells
contagious examples in animals
Devil Facial Tumor Disease
Clams
Dogs Canine transmissible venereal tumor
Sharks
animal immune to cancer
Naked mole rats
high molecular mass hyaluronan
prevents cells from overcrowding and forming tumors
people immune to cancer
Laron syndrome
significantly reduced risk
insuring like growth factor IGF-1
p53
during g1 this tumor suppressor protein triggers cdk inhibitor protein production these proteins bind to cdk cyclin complexes which are needed to move to s phase buying time for DNA to repair
apoptosis
automated cell death when DNA can’t be repaired or passed on
benign tumor
remains where it grew and usually not dangerous
cells are normal and capsulated non- cancerous
malignant tumor
can invade surrounding tissue cells have large dark nuclei and may have an abnormal shape
metastic
a second tumor spread from cells of primary
most cancer deaths are due to metastasis distant from original tumor
angiogenesis
cells recruiting blood vessels so they can grow and spread the tumor
cancerous cell division
uncontrollable with no signals needed from other cells to divide
Henrietta Lacks
1951 her cells were collected after she died from cervical cancer and studied. Today more of her cells are alive than when she was alive. Moved forward cancer research
Radiation
uv radiation in sunlight
skin cancer
Human papilloma virus
passed through sex can lead to cervical cancer recommended to get vaccinated
carcinogen
cancer causing agent
