common neurological conditions lecture Flashcards
4 most common
migraine
parkinsons
epilepsy
MS
common migraine
no aura
fx of migraine
aura
sx of 20m to 60m - nil else gives a set of symtoms for this duration
movement exacerbates
photophobia
phonophobia
hyperosmia
nausea - relief versus anti-emetics
allodynia - pain due to stimulus that does not normally provoke pain
types of aura
zigzag strcutre
negative scotoma
positive scotoma
loss vision one sided
hemiplegic migraine
aura - hem sensory loss or weakness - start in face
headache often mild and ipsilateral to sx
may be familial
tx of acute migraine attack
aspirin 600-900mg
anti emetic
NSAID - ibruprofne and nurofen
triptans
triptans
agonist 5
prophylactic
proranolol - non slective if cardioselective horrifc
tricyclics
valporate
verapamil
candesartan
pizotifen
GONI - greater occipital nerve injections
topomax - topiramate - 2nd line in formula - can cause anorexia and contraindicated in glaucoma - not in child bearing age women
Bonta - botoz
anti- CGRP antagonists - end pathway of migraine blockade - can get constipated
botox in what nerve as tx for migraine
greater and lesser occipital nerve
parkinson disease
substantia nigral dopaminergic neuronal loss
non motor sx of parkinsons
depressions , constipation, sleep disturbances and olfactory dysfunction
bradykinesia
lose the amplitude of the action - movement becomes slower and and smaller.
expyramidial rigidity
cogwheel rigidity
tx parkinsons
physcial activity
l dopa side effects
psychiatric sx linked to depression
N&V
prolonged use can cause wearing off effect