amino acid, peptides, and proteins Flashcards

1
Q

What are alpha amino acids? What two function groups do they have?

A

Molecules that build proteins and enzymes. Carboxylic acid and amino group

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2
Q

How many common amino acids are there are how many are essential?

A

20 common, 10 essential

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3
Q

What type of amines are amino acids?

A

Primary, except for one

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4
Q

What is the Zwitterion?

A

How amino acids are found in nature, O of carboxylic acid has negative charge and amine has positive charge

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5
Q

Do all L amino acids have a stereocenter?

A

Yes, except for one

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6
Q

What is the stereochemistry of all amino acids?

A

S

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7
Q

How do we determine if amino acids are D or L?

A

Location of the amine group in the fisher projection. On the left is L, right is D

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8
Q

What happens when you put an amino acid under acidic or basic conditions?

A

Acidic- protonates O of carboxylic acid. Charge on amine remained
Basic- deprotonates N of amine. Charge on carboxylic acid O remains charged

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9
Q

Why can you not put carboxylic acid and amine together to form an amine?

A

Because carboxylic acid is acidic and amine is basic so it forms acid base reactions charging both functional groups

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10
Q

What is the pH of an all protonated amino acid?

A

1-3, acidic

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11
Q

What is the pH of an all deprotonated amino acid?

A

8-12, basic

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12
Q

What is the pH of the Zwitterion? What is this point called?

A

5-7, neutral, isoelectric point

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13
Q

What is the more acidic group of the all protonated amino acid? Why?

A

OH, it gives off the H first

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14
Q

What are peptides and proteins? What is the difference?

A

Amino acid polymers. Few= peptide, Many=protein

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15
Q

What are peptides and proteins composed of?

A

Amino acid units (residues) that are linked by peptide bonds

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16
Q

How can two amino acids be linked?

A

Will have a N term and C term. Either on either side. Amide bond between them. N and O will have charge at either end