Chapter 29 : Sulfonamides And Nitroimidazoles antibiotics Flashcards
What is sulfonamides used for?
( it’s a type of antibiotic )(2)
MRSA & urinary tract infections
Sulfonamides is normally the first group of antibiotics but it’s often combined with another antibiotic, why?
Because it works better
What’s the main medication that helps cure out patients with staphylococcus infections? That is sulfonamides?
Sulfamethoxazole/trimethoprim
Sulfonamides can be used how ? (2)
Systemic or topical
Normally we don’t really like giving sulfonamides is because?
Allergies are super common to get or develop
What are some common side effects of sulonamides? (5)
Photosensitivity
Crystals in urine
Steven’s Johnson syndrome
Blood dyscrasias
( bone marrow suppression & anemic )
Hepatic necrosis
Since this causes patients to get crystals in their urine, what will we tell them?
Drink more water!
What is Steven Johnson syndrome?
Acute destruction of epithelium of skin and mucous membranes
When does Steven Johnson syndrome occur?
Behind 4-21 days after starting med
How does Steven Johnson syndrome look ?
Start to end
Macular rash but quickly changed to sheets of skin peeling off
( starts off like feeling bad )
Sulfa drugs interactions
Enhances effects of ___
Increases risk of ___
Can cause ___
Renal elimination can be increase by___
Oral anticoagulants
Methotrexate toxicity
Phenytoin toxicity
Acidifying urine
What are we going to educate our patient on when on sulfas?? (4)
Drink 2000-3000 water
Take with food
Don’t take with antacids
Sunglasses!!
What are we going to take before putting a patient on sulfa medications and why?
CBC baseline
Since it causes blood dyscrasis ( anemic )
What are examples of Nitroimidszoles?
Metronidazole ( flagyl)
Tinidazole
Secnidazole
What does nitromidazoles treat?
CDIFF!!!!!
H.pylori
