Acute Kidney Injury (AKI) Flashcards

1
Q

What is acute kidney injury related to

A

a rapid decrease in renal function

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2
Q

What does acute kidney injury cause

A

rapid decrease in renal function, accumulation of waste, fluid and electrolyte imbalances

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3
Q

How long does AKI take to heal

A

2 weeks to 3 months with proper interventions

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4
Q

Etiology of AKI

A

reduced renal blood flow –> decreased GFR, accumulation of nitrogenous wastes, impairment of fluid and electrolyte balance

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5
Q

Why is AKI common in critical cases

A

sepsis, multifactoral etiologies

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6
Q

Classifications of AKI

A

pre, intra, post

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7
Q

4 pathophysiologic stages of AKI

A

initial, oliguria, diuresis, recovery

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8
Q

Initial stage of AKI

A

time of precipitating insult to the time of clinical manifestations, lasting hours to days

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9
Q

Oliguria stage of AKI

A

significant decrease in GFR and urine output

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10
Q

What does oliguria cause

A

retention of urea, fluid, potassium, sulfate, creatinine

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11
Q

When and where does inflammation begin

A

Oliguria stage of AKI, nephrons

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12
Q

Diuresis stage of AKI

A

kidneys are beginning to recover from the initial insult

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13
Q

What increases during diuresis

A

urine output, mostly dumb urine

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14
Q

What is dumb urine

A

urine without adequate filtration

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15
Q

Recovery stage of AKI

A

the time needed for final repair of renal damage

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16
Q

What starts the recovery stage of AKI

A

onset of increased urine output

17
Q

What signifies normal kidney function

A

appropriately concentrated urine

18
Q

What is clinical presentation influenced by

A

the cause of the injury

19
Q

What symptoms always occur in AKI

A

oliguria and fluid overload

20
Q

What causes signs and symptoms of uremia

A

nitrogenous waste builds up

21
Q

Encephalopathy clinical manifestations

A

confusion, disorientation, stupor, coma

22
Q

Thrombocytopenia clinical manifestations

A

bruising and spontaneous bleeding due to low hemoglobin

23
Q

Anemia clinical manifestations

A

fatigue, weakness, dyspnea, pale color

24
Q

Hyperkalemia clinical manifestations

A

cardiac dysrhythmias and extreme muscle weakness

25
Q

Metabolic acidosis clinical manifestations

A

tachypnea, headache, confusion, weakness, nausea, vomiting

26
Q

Hypocalcemia clinical manifestations

A

bone breakdown, neuromuscular tetany, seizures

27
Q

How is AKI diagnosed

A

urinalysis, imaging, ABGs, CBC