SAVES

Question 1

SAVES definition

Answer 1

-Structure analysis and verification server

• SAVESv6.0- structure validation server (ucla.edu)
• collection of webbased tools
• assess/analyse and validate quality of 3d protein models (gotten by experimental and computational methods)

Question 2

Purpose

Answer 2

-check the reliability and quality of the protein model

Question 3

Components of SAVES

Answer 3

• WHAT IF SERVER- checks stereochemical quality (bond length, angle, torsion angles etc)

-PROCHECK - checks stereochemical quality and generates ramachandran plots

• ERRAT- checks overall quality of protein by analyzing the distribution of atomic coordinates in protein

-VERIFY3D
-PROVE

Question 4

Usage

Answer 4

• input PDB structures
• uses specialized algorithms and evaluates structure quality
• gives summary of the protein structure
• can identify errors and inaaccuracies in proteins

Question 5

Community impact/benefits

Answer 5

-imp for structural biologists, computational biologists and bioinfomaticians

-checks reliability, quality and integrity of protein structures deposited in PDB

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