LABA/LAMA combo, LABA/LAMA/ICS combo, and mast cell stabilizer Flashcards

1
Q

olodaterol/tiotropium brand

A

stiolto respimat

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2
Q

olodaterol/tiotropium (stiolto respimat) dosage form

A

respimat
2.5 mcg/2.5mcg/inhalation

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3
Q

vilanterol/umeclidinium brand

A

anoro ellipta

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4
Q

vilanterol/umeclidinium (anoro ellipta) dosage form

A

ellipta
62.5mcg/25mcg/inhalation

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5
Q

indacaterol/glycopyrronium brand

A

utibron neohaler

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6
Q

indacaterol/glycopyrronium (utibron neohaler) dosage form

A

neohaler
27.5mcg/15.6mcg capsules

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7
Q

formoterol/glycopyrronium brand

A

bevespi aerosphere

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8
Q

formoterol/glycopyrronium (bevespi aerosphere) dosage form

A

aerosphere
4.8mcg/9mcg/inhalation

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9
Q

formoterol/aclidinium brand

A

duaklir pressair

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10
Q

formoterol/aclidinium (duaklir pressair) dosage form

A

DPI
12mcg/400mcg/actuation

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11
Q

olodaterol/tiotropium (stiolto respimat) dosing in adults

A

two inhalations qd
COPD only

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12
Q

vilanterol/umeclidinium (anoro ellipta) dosing in adults

A

one inhalation qd
COPD only

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13
Q

indacaterol/glycopyrronium (utibron neohaler)

A

contents of one capsule bid
COPD only

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14
Q

clinical pearls of LABA/LAMA combo

A

see individual products for side effect profile
not indicated for treatment of acute deteriorations
COPD only

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15
Q

formoterol/glycopyrronium (bevespi aerosphere) dosing in adults

A

two inhalations BID
COPD only

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16
Q

formoterol/aclidinium (duaklir pressair) dosing in adults

A

one inhalation bid
COPD only

17
Q

LABA/LAMA combos

A

olodaterol/tiotropium (stiolto respimat)
vilanterol/umeclidinium (anoro ellipta)
indacaterol/glycopyrronium (utibron neohaler)
formoterol/glycopyrronium (bevespi aerosphere)
formoterol/aclidinium (duaklir pressair)

18
Q

LABA/LAMA/ICS combos

A

fluticasone/umeclidinium/vilanterol (trelegy ellipta)
budesonide/glycopyrrolate/formoterol fumarate (breztri aerosphere)

19
Q

fluticasone/umeclidinium/vilanterol brand

A

trelegy ellipta

20
Q

fluticasone/umeclidinium/vilanterol (trelegy ellipta) dosage form

A

ellipta
100-62.5-25mcg/inhalation
200-62.5-25mcg/inhalation

21
Q

budesonide/glycopyrrolate/formoterol fumarate brand

A

breztri aerosphere

22
Q

budesonide/glycopyrrolate/formoterol fumarate (breztri aerosphere) dosage form

A

aerosphere
160mcg/9mcg/4.8mcg/inhalation

23
Q

fluticasone/umelcidinium/vilanterol (trelegy ellipta) dosing in adults

A

asthma - one inhalation qd (two available doses)
COPD - one inhalation qd (only lower dose)

24
Q

budesonide/glycopyrrolate/formoterol fumarate (breztri aerosphere) dosing in adults

A

two inhalations bid
COPD only

25
Q

adverse effects of LABA/LAMA/ICS combo

A

see individual products

26
Q

cromolyn brand

A

intal

27
Q

cromolyn (intal) dosage form

A

nebulizer solution
20mg/ampule

28
Q

cromolyn (intal) dosing in 0-4 yos

A

one ampule qid
safety/efficacy not established in children under 2 yos

29
Q

cromolyn (intal) dosing in 5-11 yos

A

one ampule qid

30
Q

cromolyn (intal) dosing in adults

A

one ampule qid

31
Q

mast cell stabalizer

A

cromolyn (intal)

32
Q

adverse effects of cromolyn (intal)

A

high incidence of unpleasant taste in mouth (over 10%)
rare cardiac arrhythmias
coughing
dyspnea
sore throat
nausea, vomiting, diarrhea if absorbed systemically

33
Q

clinical pearls of cromolyn (intal)

A

less effective than low-dose ICS
prevents increase in bronchial hyperreactivity seen in allergy season