Acid Phosphatase (ACP) Flashcards
Acid phosphatase is also known as
A. Orthophosphoric Monoester
B. Orthophosphoric Monoester Phosphohydrolase
B. Orthophosphoric Monoester Phosphohydrolase
A hydrolase that works in acidic pH
A. Alp
B.acp
B. Acp
ACP has Same function and activity as —-
ALP
Liberate inorganic phosphate from an organic phosphate ester with production of alcohol
A. Alp
B. Acp
B. Acp
Tissue sources of ACP ENUMERATE 4
- Prostate gland (male patient)
- Bones (osteoclast)
- RBCs
- Thrombocytes (platelets)
”RT PB”
Also found in Seminal fluid
ACP
Specimen used in acp to investigate sexual assault
Vaginal washing
ACP activity in seminal fluid could persist for up to —-
A.4 days
B.72 hours
C. 24 hrs
A and B
For evaluation of metastatic carcinoma of prostate
a. Decrease acp
B. Increase acp
B. Increase acp
More specific and sensitive marker for prostate
PSA
2 Chemical inhibitors in acp
A. L-tartrate ions and Shinowara
B. L-tartrate ions and formaldehyde
C. L-tartrate ions and formaldehyde and cupric
C
inhibits specific prostatic ACP
a) L-tartrate ions
b) Formaldehyde and Cupric ions
a) L-tartrate ions
inhibits red cell ACP
a) L-tartrate ions
b) Formaldehyde and Cupric ions
b) Formaldehyde and Cupric ions
Reaction PRODUCT OF ACP
A.p- Nitrophenol+ phosphate ion
B. p- Nitrophenol+ phosphate ion+ NAD
A.p- Nitrophenol+ phosphate ion
ACP
Quantitative end point substrate
A. Α-naphthyl phosphate
B. Thymolphthalein monophosphate
B. Thymolphthalein monophosphate
