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Clinical Chemistry II > Endocrinology MCQ > Flashcards

Endocrinology MCQ Flashcards

1
Q

TSH is produced by the:

A

Pituary Gland

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2
Q

The major control mechanism for serum calcium level is played by

A

Parathyroid hormone

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3
Q

Persistent hypoglycemia is seen in which of the following conditions?
1. insulinoma
2. galactosemia
3. Hyperthyroidism
4. Addison’s disease

A

1 and 2

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4
Q

One of the following is NOT secreted by the anterior pituitary gland. Which one is it?

A

VMA

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5
Q

Increased urinary catecholamine metabolites with intermittent hypertension may indicate which of the following conditions:

A

B. adrenal medullary disease

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6
Q

The major thyroid hormone is

A

Thyroxine

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7
Q

Plasma renin activity is most useful in the differential diagnosis of:

A

Hypertension

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8
Q

Assessments of primary & secondary hypothyroidism include the following EXCEPT:

A. T 3 C. TSH
B. T 4 D. Calcitonin

A

Calcitonin

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9
Q

The reference method for pituitary secretions is the

A

RIA TECHNIQUES

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10
Q

The secretion of anterior pituitary hormones is regulated by:

A

Hypothalamus

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11
Q

Which of the following is caused by oversecretion of the adrenal cortex?

A

Cushing’s disease

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12
Q

The use of iodized salt serves to provide iodine for the synthesis of:

A

Thyroid hormone

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13
Q

Diurnal variations is important to consider when collection blood for the assay of:

A

Cortisol

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14
Q

The estrogen designated as E 2 whose urine concentration is the greatest is:

A

Estradiol 17β

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15
Q

What is the hormone which controls the reabsorption of sodium in the kidneys:

A

Aldosterone

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16
Q

Catecholamines are secreted by the:

A

Adrenal medulla

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17
Q

Which of the following is a metabolite of epinephrine?

A

Vanillylmandelic acid

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18
Q

Patient has a TSH result markedly elevated. This maybe due to:

A

Hyperthyroidism

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19
Q

Patient’s value is normal T 3 , T 4 , what do you think is the value of TSH?

A

Normal

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20
Q

In which of the following are the thyroid hormones classifieed?

A

Amino acid derivatives

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21
Q

When is the best time to get plasma cortisol samples

A

8 am

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22
Q

Why is it important to time samples for cortisol level:

A

Because maximal secretion of cortisol has a diurnal pattern

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23
Q

The relationship of a cholesterol and thyroid hormone is:

A

Inversely proportional

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24
Q

Diabetes insipidus is associated with deficiency in

A

ADH

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25
Q

TRH is produced by the:

A

Hypothalamus

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26
Q

Calcium concentration in the serum is regulated by:

A

Parathyroid hormone

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27
Q

Which of the following steroids is an adrenal cortical hormone?

A

Corticosterone

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28
Q

Which of these hormones are especially related in the delicate balance of production and utilization of glucose in the body?

A

Insulin and glucagon

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29
Q

Which of the reactions measures 17-ketosteroids?

A

Zimmerman

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30
Q

The net effect of calcitonin on the metabolism of calcium and calcium and phosphorus is:

A

Decreased calcium, increased phosphorus

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31
Q

Patients with Cushing’s syndrome exhibit:

A

serum cortisol concentrations greater than 15 mg/dL

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32
Q

Fasting serum phosphate concentration is controlled primarily by the :

A

Parathyroid glands

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33
Q

A patient has the following test results: Decreased serum calcium levels Increased serum phosphorous levels Decreased levels of parathyroid hormone
This patient most likely has:

A

Hypoparathyroidism

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34
Q

The Porter-Silber reaction is used in the assay of:

A

Glucocorticoids

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35
Q

ACTH is produced in:

A

Adenohypophysis

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36
Q

This hormone is produced by the posterior pituitary gland:
A. Vasopressin C. Prolactin
B. Both A & D D. ADH

A

Both A and D

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37
Q

Serotonin is secreted by the:

A

Small intestine

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38
Q

Dark-light cycle is an important function of:

A

Melatonin

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39
Q

Glucagon is produced by:

A

Alpha cell of the pancreas

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40
Q

ACTH acts on the:

A

Adrenal cortex

41
Q

The Zimmerman determination of 17-ketosteroid is based on reaction with:

A

Meta-dinitrobenzene

42
Q

Which of these hormones lowers the blood glucose level?

A

Insulin

43
Q

At low or absent levels, which one of the following hormones has the ability to produce hyperglycemia:

A

Insulin

44
Q

Which of these have receptors for ADH?

A

DCT

45
Q

One of the following is NOT secreted by the adenohypophysis. Which one is it?

A

hcg

46
Q

The main thyroid hormone is

A

T3

47
Q

Elevated serotonin metabolites may indicate which of the following?
A. Idiopathic hypertension
B. Pheochromocytoma
C. Diabetes mellitus
D. Intestinal cancer

A

Intestinal Cancer

48
Q

Hypothyroid test is shown in

A. Normal T 3
B. Normal Free T 4 level
C. Decrease T 3 , increase T 4
D. Decrease resin T 3 T 4

A

Decrease T 3 , increase T 4

49
Q

The androgen whose urine concentration is the greatest is:

A

Testosterone

50
Q

What is the hormone which controls the natriuresis in the Kidney:

A

ANF

51
Q

Erythropoietin is secreted by the:

A

Kidney

52
Q

Which of the following is a metabolite of serotonin:

A

5’-HIAA

53
Q

Which is an advantage of RIA assay over other tests for hormones?

A

High specificity

54
Q

Patient has a TRH result that is markedly elevated. This maybe due to:

A

Primary hypothyroidism

55
Q

Patient’s T 3 , & T 4 levels are low, what do you think is the value of TSH?

A

Increase

56
Q

which of the following are the eicosanoids classified?

A. Amino acid derivatives
B. Steroid hormones
C. Fatty acid derivatives
D. Peptide hormone

A

Fatty acid derivatives

57
Q

deficiency of somatotropin will result in

A

Dwarfism

58
Q

The tumor marker associated with ovarian carcinoma is:

A

HcG

59
Q

When is the best time to get plasma testosterone samples:

A

6 am

60
Q

Which of these hormones are especially related in the delicate balance of production and utilization of glucose in the body?

A

Growth hormone and cortisol

61
Q

Which of the reactions measures 17-OHcorticoteroids?

A

Porter-Silber

62
Q

net effect of calcitonin on the metabolism of calcium and phosphorus is:

A

Decreased calcium, increased phosphorus

63
Q

The Kober reaction is used in the assay of:

A

Urinary estrogen

64
Q

The estrogen whose urine concentration is elevated in gestation is:

A

Estriol

65
Q

What is the hormone which controls the reabsorption of water in the Kidney:

A

ADH

66
Q

ACTH is produced in:

A

Adenohypophysis

67
Q

This hormone is produced by the posterior pituitary gland:

A. Vasopressin C. Prolactin
D. ADH

A

B. Both A & D

68
Q

Catecholamines are secreted by the:

A

Adrenal Medulla

69
Q

The menstrual cycle is important to consider when collection blood for the assay of:

A

Gonadotropins

70
Q

GHRH is produced in:

A

Alpha cell of the pancreas

71
Q

ACTH acts on the:

A

Adrenal Cortex

72
Q

The Zimmerman determination of 17-ketosteroid is based on reaction with:

A

Meta-dinitrobenzene

73
Q

Which of these hormones lowers the blood glucose level?

A

Insulin

74
Q

At low or absent levels, which one of the following hormones has the ability to produce hyperglycemia:

A

Insulin

75
Q

The major control mechanism for serum calcium level is played by

A

Parathyroid hormone

76
Q

Persistent hypoglycemia is seen in which of the following conditions?

  1. insulinoma
  2. galactosemia
  3. hypothyroidism
  4. Addison’s disease
A

insulinoma
2. galactosemia
3. hypothyroidism
4. Addison’s disease

77
Q

Normal thyroid function is termed

A

Euthyroidism

78
Q

Which of these have receptors for ADH?

A

DCT

79
Q

One of the following is secreted by the neurohypophysis. Which one is it?

A

Oxytoxin

80
Q

Increase values of Thyroxine (T 4 -RIA) is usually associated with the following, EXCEPT:

A

Nephorosis

81
Q

Elevated serotonin metabolites may indicate which of the following?

A

Intestinal Cancer

82
Q

Plasma renin activity is most useful in the differential diagnosis of:

A

Hypertension

83
Q

Following are thyroid function test, EXCEPT:
A. Free thyroxine T 4 C. Thyroglobulin B. Free Triodothyronine D. Testosterone

A

Testosterone

84
Q

Estrogen and progesterone receptor assays are useful in assessing prognosis in which of the following:

A

Cancer of the uterus

85
Q

One of the following is NOT associated with hyperthyroidism;

A

Decreased calcium

86
Q

One of the following is not thyroid function test:

A.T3 C.TSH
B.T4 D.ACTH

A

ACTH

87
Q

Which hormone is responsible for calorigenesis and thermogenesis?

A

T4 and T3

88
Q

The secretion of anterior pituitary hormones is regulated by:

A

Hypothalamus

89
Q

Which of the following is caused by versecretion of the thyroid gland?

A

Graves disease

90
Q

The major nonspecific binding protein for hormones is:

A

Albumin

91
Q

T 3 uptakes is actually a measurement of:

A

Thyrotoxicosis

92
Q

The major androgen produced in adrenals is:

A

DHEA

93
Q

Which of the following is a metabolite of epinephrine

A

Vanillylmandelic acid

94
Q

Patient has a TSH result that is markedly elevated. This maybe due to:

A

Primary hypothyroidism

95
Q

Patient’s T 3 , & T 4 levels are normal, what do you think is the value of TSH?

A

Increased

96
Q

which of the following is melatonin hormone classified?

A

Amino acid derivatives

97
Q

The deficiency of the thyroid hormone in children is known as

A

Cretinism

98
Q

What hormone is responsible for circadian rhythm:

A

Melatonin

Clinical Chemistry II (45 decks)

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