Subcutaneous fungal infections (Fungal skin infections)

Question 1

Background

Answer 1

involve the deeper layers of the skin (dermis, subcutaneous tissue and bone. causative organisms normally live in the soil and enter the body through an injury and stay localised at the site of implantation

2 common types:
mycetoma (eumycetoma) chronic infection of the SC tissue of the foot

Chromoblastomycosis: affects the skin and SC tissue of the limbs. organism is inoculated into the skin by a minor injury.

Question 2

Signs and Symptoms / Diagnosis

Answer 2

mycetoma:
discharging sinuses filled with organisms

Chromoblastomycosis:
raised crusted lesions

Question 3

Treatment

Answer 3

mycetoma:
itraconazole and ketoconazole

chromoblastomycosis:
Itraconazole and ketoconazole are used
ALT local heat, cryotherapy or surgery to remove the affected tissue completely will be used.