Endocrine Drugs Flashcards
Name the 2 drugs used to treat hypothyroidism
1.LIOTHYRONINE(T3)… IV-emergency use,fast onset but short acting
2.LEVOTHYROXINE(T4)…oral prodrug,long acting
Name drugs used to treat hyperthyroidism
1.CARBIMAZOLE… prodrug,take long to act
2.PROPYLTHIOURACIL…works rapidly
* the 2 are thyroperoxidase inhibitors
3.PROPANOLOL… beta blocker since tachycardia is one of the symptoms
How do you treat hyperthyroidism for patients with neutropenia & agranulocytosis
Use BLOCK & REPLACE method,block insulin release totally and use LEVOTHYROXINE to replace it
*symptoms if the 2 conditions; sore throat
Rash
Headache
Joint pain
Name the 2 drugs used to treat Addison’s disease( adrenal deficiency)
1.HYDROCORTISONE( glucocorticoid)…. Synthetic cortisol
2.FLUDROCORTISONE(mineralocorticoid)….unnecessary for pituitary failure
Glucocorticoids drugs are used bcz of their anti-inflammatory & immunosuppressive effects,name these drugs;
1.HYDROCORTISONE…topical use
2.PREDNISOLONE…oral
3.BETAMETASONE
4.DEXAMETASONE
5.BECLOMETASONE…topical use
Name the 2 glucocorticoids drugs used to treat asthma
1.FLUTICASONE…inhaled in STEP 2
2.PREDNISOLONE…oral in STEP 5
If oral steroids such as PREDNISOLONE are abruptly withdrawn,what problems can this cause?
Hypotension
Fever
Weight loss
* hence if more than 3 weeks of use,DO NOT withdraw corticosteroids abruptly
What are the adverse effects of using MINERALOCORTICOIDS such as fludrocortisone?
Fluid retention
Hypertension
K/Ca loss
What are the adverse effects of using glucocorticoids
Diabetes
Osteoporosis
Muscle wasting
Peptic ulcer
Cushing’s syndrome
What is ADH used to treat
DIABETES INSIPIDUS
Name an adh type drug used to treat Syndrome of inappropriate ADH secretion(SIADS)
TOLVAPTAN
* a V2 receptor antagonist
Name ADH type drugs used to treat DIABETES INSIPIDUS
DESMOPRESSIN(V2)
CARBAMAZEPINE(anti epileptic)
THIAZIDE(diuretic)
Terlipressin…vasoconstriction(v1)
What oxytocin type drug is used to prevent premature labor
ATOSIBAN
Name the Prostaglandin E1 analogue drug,used for early therapeutic ABORTION
MISOPROSTOL
What is DINOPROSTONE(PGE2) drug used for
Induce labor
Induce late therapeutic abortion
