Oxytocics💥💥

Question 1

What is oxytocic

Answer 1

Are drugs of varying chemical nature that excite uterine contractions
Eg oxytocin, ergot derivatives, prostaglandins

Question 2

Origin of oxytocin

Answer 2

Oxytocin is synthesized in the paraventricular nuclei of the hypothalamus.
T½= 3-4mins

Question 3

Briefly explain the mode of action of oxytocin

Answer 3

During labour oxytocin increases myometrial oxytocin receptors
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Oxytocin acts through the oxytocin receptors and
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Stimulate amniotic and decidual prostaglandins production and initiate myometrial contractions

Question 4

State the types/ preparations of oxytocins

Answer 4

1. Synthetic oxytocin
   Also called “pitocin”
   Which is widely used, it had oxytocin oxytocic effect but no vasopressor action.
   51.U/ml
2. Syntometrine
   Also called “sandox”. is a combination of 5units of syntocinon and 0.5mg ergometrine.
3. Desamino oxytocin
   Which is more effective than oxytocin.
   Buccal tablets contains 501.1

Oxytocin nasal solution contains 40units/ ml

Question 5

State the routes of administration of oxytocin

Answer 5

IV/IM
buccal
Nasal spray

Question 6

State the indications for oxytocin

Answer 6

Used in
1. Pregnancy
2. Labour
3. Puerperium
It can be diagnostic
Or
Therapeutic use

Question 7

Therapeutically oxytocin is used for__________

Answer 7

1.pregnancy
2. labour
3. Puerperium

Question 8

In pregnancy oxytocin is used to

Answer 8

1. Accelerate abortion
2. Stop bleeding
3. Induce labour
4. Facilitate cervical ripening for labor

Question 9

In labour oxytocin is used to

Answer 9

1. Active management of the 3rd stage of labor
2. Expulsion of placenta as an alternative to ergometrine

Question 10

In puerperium oxytocin is used to

Answer 10

1. Minimise blood loss to control PHH

Question 11

Diagnostically oxytocin is used in

Answer 11

1. Contractions stress test
2. Oxytocin sensitivity test

Question 12

State the contraindications of oxytocin in pregnancy

Answer 12

1. Grand multipara
2. Contracted pelvis
3. History if CS or hysterectomy
4. Malpresentation

Question 13

State the contraindications of oxytocin in labor

Answer 13

1. Grand multipara
2. Contracted pelvis
3. History of CS or hysterectomy
4. Malpresentation
5. Obstructed labor
6. Uncoordinate uterine action
7. Fetal distress

Question 14

State other contraindications of oxytocin

Answer 14

1. Hypovolemic state
2. Cardiac disease

Question 15

State the dangers of oxytocin to the maternal health

Answer 15

1. Uterine hyper stimulation
2. Uterine rupture
3. Water intoxication

Question 16

What is the danger of oxytocin to the fetal

Answer 16

Fetal distress or death