13 - Pedi Neuro

Question 1

time frame for sydenham’s chorea

Answer 1

starts 4-8 wks after group A strep infxn

usually lasts 2-6 mo, almost always < 2 yrs

Question 2

chorea minima

Answer 2

comorbidity of ADHD, often seen in Tourette synd

benign (but can interfere w/ fine motor skills)

Question 3

NMDA encephalitis

Answer 3

IgG to NMDA receptor
MC autoimmune encephalitis
AMS > seizures > dyskinesia (facial stereotypies MC)
tx w/ intensive prolonged steroids, IVIG, immune modulation

Question 4

characteristics of dystonia

Answer 4

involuntary / insuppressable
stereotyped, twisting
exacerbated by volitional mvmt or emotion
hypertonia during mvmt (baseline tone can be nl)
reflexes nl to inc

Question 5

dyskinetic CP

Answer 5

varied mvmts - dystonia, chorea, athetosis, ballism
avg IQ** often unrecognized though
major causes - kernicterus, near term hypoxia, basal ganglia CVA

Question 6

Opsoclonus myoclonus

Answer 6

assoc w/ neuroblastoma

twitching of face/eyes and feet

Question 7

hyperekplexia

Answer 7

excessive startle response
non extinguishable glabella reflex
often causes tonic posturing