Gastrointestinal Trophoblastic Disease

Question 1

This is the most curable gynecologic malignancy due to high sensitivity to chemotherapy?

Answer 1

Gestational trophoblastic disease

Question 2

Which entity has the highest sensitivity to chemotherapy?

Answer 2

Gestational trophoblastic disease

Question 3

Which ethnicity has the highest reported GTD?

Answer 3

Southeast Asian & Japanese Women

Question 4

What is the most common karyotype for complete moles ? Incomplete moles?

Answer 4

Complete : 46 XX
Incomplete: 69 XXX/ YYY

Question 5

What is the most common presentation for gestational trophoblastic neoplasia?

Answer 5

Abnormal uterine bleeding >6weeks following pregnancy

Question 6

Pathologic criteria for complete mole?

Answer 6

Diffuse hydropic villi and marked trophoblastic proliferation

Question 7

Races with greater risk for developing hydatidiform mole?

Answer 7

Asian, Hispanics, and American Indians Extremes of Reproductive Age Prior Hydatidiform Mole