Post Partum Care

Question 1

Brexanolone is

Answer 1

Allopregnanolone
Given IV
Modulator of GABA-a receptors
Used to treat postnatal depression

Question 2

Zuranolone is

Answer 2

Allopregnanolone
Neuroactive steroid
GABA-A receptor modulator

Question 3

Pain management after c/s

Answer 3

Intrathecal diamorphine max 300 mcg or 3mg via epidural OR

Intrathecal morphine 100mcg + 15mcg fentanyl or 3mg morphine via epidural

Oral morphine sulfate, paracetamol and ibuprofen +/- dihydrocodeine
Tramadol or oxycodone if not sufficient

Question 4

C/S wound care

Answer 4

Negative pressure wound therapy if BMI >35

Remove dressing 6 to 24 hours after

Question 5

Risk of stress incontinence after c/s

Answer 5

4%