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pharma > CNS > Flashcards

CNS Flashcards

1
Q

analeptics or convulsants

A. Cns
B. Opiods

A

CNS STIMULANTS

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2
Q

effect of blockade of transmitter catabolism inside nerve terminal

A

PRESYNAPTIC SITES

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3
Q

effect of blockade of reuptake or degradation

A

PRESYNAPTIC SITES

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4
Q

receptor antagonism is a common mechanism of action for CNS drugs

A

POSTSYNAPTIC SITES

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5
Q

Theophylline
Theobromine

Caffeine

A

METHYLXANTHINES

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6
Q

most widely used psychoactive drug in the world

A

CAFFEINE

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7
Q

→ 2nd to caffeine as most widely used CNS stimulant
→ 2nd to alcohol as most abused drug

A

NICOTINE

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8
Q

an inactive metabolite, can be used as a measure of smoking habits.

A

Cotinine

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9
Q

blocks the reuptake of monoamines

A

COCAINE

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10
Q

powerful stimulant

A

COCAINE

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11
Q

“fight/flight” syndrome

A

COCAINE

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12
Q

o major urinary metabolite

o can be found in the urine for 2-5 days after a binge

A

benzoylecgonine

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13
Q

detects cocaine use

A

benzoylecgonine test

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14
Q

has a significant teratogenic effect on the fetus

A

COCAINE

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15
Q

freely penetrates the BBB

A

AMPHETAMINE

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16
Q

used to be utilized as an appetite suppressant in obese
patients; because of its congenital anomalies, it was discontinued in such cases

A

AMPHETAMINE

17
Q

USES
→ in an ADHD-child that is hyperkinetic & lacks the ability to be involved in any one activity for longer than a few minutes

A

AMPHETAMINE

18
Q

derivative of amphetamine

A

methylphenidate

19
Q

most commonly used & abused psychomotor stimulant

A

METHAMPHETAMINE

20
Q

Shabu

A

METHAMPHETAMINE

21
Q

ecstasy

A

3,4-METHYLENEDIOXYMETHAMPHETAMINE

22
Q

preferential affinity for serotonin transporter → increasing
serotonin concentration

A

3,4-METHYLENEDIOXYMETHAMPHETAMINE

23
Q

excess water intake & water retentions → “water intoxication” → coma

A

3,4-METHYLENEDIOXYMETHAMPHETAMINE

24
Q

psychedelic agents or psychomimetic drugs

A

HALLUCINOGENS

25
Q

ability to alter consciousness such that the individual senses things that are not present

A

HALLUCINOGENS

26
Q

have a high affinity for 5-HT2 receptors

A

HALLUCINOGENS

27
Q

profoundly alters human behavior, eliciting sensory distortion (especially visual) and hallucinations

A

LYSERGIC ACID DIETHYLAMIDE (LSD)

28
Q

most potent hallucinogenic

A

LYSERGIC ACID DIETHYLAMIDE (LSD)

29
Q

main psychoactive alkaloid in marijuana

A

TETRAHYDROCANNABINOL (THC)

30
Q

cannabinoid receptors
o G protein coupled receptors

A

TETRAHYDROCANNABINOL (THC)

31
Q

has antiemetic action

A

TETRAHYDROCANNABINOL

32
Q

“angel dust”

A

PHENCYCLIDINE (PCP)

33
Q

5HT, 5-hydroxytryptamine

A

SEROTONIN

34
Q

synthesized from tryptoph

A

SEROTONIN

35
Q

found in high concentration in enterochromaffin cells of the GIT,
storage granules of platelets, CNS

A

SEROTONIN

36
Q

(+) chronotropic & inotropic actions

A

SEROTONIN

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