Lung Cancer

Question 1

Paraneoplastic syndromes

Answer 1

• From SCLC tumor hormone secretion
• ACTH = Cushing
• ADH = SIADH, edema, diluted electrolytes
• FSH = Gynecomastia
• PTH = Hypercalcemia
• Ectopic insulin lowers glucose

Question 2

Lung cancer warning signs

Answer 2

• Hoarse voice
• RR change
• Persistent cough
• Cough change
• Rusty sputum
• Chest pain/tight
• Bronchitis recurring
• Fever +2 other signs
• Wheezes
• Clubbing
• Muffled heart sounds
• Pleural friction rub
• Fremitus
• Bone pain
• SVC syndrome (emergency)