Drug Bug Cheat Sheet Flashcards
When you see…
MSSA
Consider using…
Oral: Cephalexin, cefadroxil, dicloxacin, augmentin
IV: Cefazolin, Oxacillin, Nafcillin
When you see…
MRSA
Consider using…
Oral: SMZ/TMP, Doxycycline, clindamycin, linezolid, tedizolid, omadacyclien, delafloxacin
(note: all oral option has IV formulas too)
IV: Vancomycin, daptomycin, telavancin, Dalbavancin, Oritavancin, Ceftaroline, Tigecycline
When you see…
Enterococci
Consider using…
Ampicillin, then vacomycin
If VRE: linezolid, daptomycin, oritavancin, tigecycline, omadacycline, eravacycline
For cytitis only: nitrofurantoin, fosfomycin
When you see…
Strep pyogenes or
Strep agalactiae
Consider using…
Penicillin
Amoxicillin
Clindamycin
When you see…
Strep. Pnuemoniae or
Viridans group streptococci
Consider using…
Ceftriaxone, Levofloxacin, amoxicillin, augmentin
note: be aware of PCN and macrolide resistance
When you see…
Listeria monocytogenes
Consider using…
Ampicillin
When you see…
PsA
Consider using…
Oral: Cipro, levaquin, Delafloxacin
IV: Zosyn, ceftazidime, ceftazidime-avibactam, cefepime, Ceftolazine-tazobactam, cefiderocol, imipenem-cilastatin +/- relabactam, meropenem, aztreonam, AMG, polymyxins
When you see…
E.coli, Klebsiella
Consider using..
Oral: Cephalexine, augmentin, TMP/SMZ, Cipro, levaquin, delafloxacin
For cystitis only: Nitrofurantoin, fosfmycin
IV: Ceftriaxone, unasyn, cefepime, zosyn, carbapenems
When you see…
ESBL Producers /Drug resistance GNR
Consider using…
Carbapenems, ceftolazane-tazobactam, ceftazidime-avibactan, meropenem-vaborbactam, imipenem–cilasttain-relebactam, cefiderocol, polymixin, AMG, tigecycoline, omadacycline
For cystitis only: Nitrofurantoin, fosfomycin
When you see..
NDM producer
Consider using…
Aztreonam + (mero/vab or CAZ/AVI)
cefiderocol
When you see..
Carbapenem resistant GNR
Consider using…
ceftolazane-tazobactam, ceftazidime-avibactan, meropenem-vaborbactam, imipenem–cilasttain-relebactam, cefiderocol, polymixin, AMG, tigecycoline, omadacycline
For cystitis only: Nitrofurantoin, fosfomycin
When you see..
Candida Albicans
Consider using…
Fluconazole
When you see..
Candida Glabarata
Consider using…
Echinocandin
but can use fluconazole if susceptible
When you see..
Candida Krusei
Consider using…
Micafungin
Anidulafingin
Caspofungin
When you see..
Candida auris
Consider using…
Micafungin
Anidulafingin
Caspofungin
When you see..
Aspergillus
Consider using…
Voriconazole
Amp + Flucyto
When you see..
Stenotropomonas
Consider using…
TMP/SMZ
Levaquin
Minocycline
When you see..
Salmonella Typhi
Consider using…
FQ
TMP/SMZ
Ceftriaxone
When you see..
Anaerobes
Consider using…
Oral: flagyl, clindamycin, augmentin, moxifloxacin
IV: Unasyn, Zosyn, cefoxitin, Cefotetan, ertapenem, tigecycline
When you see..
C.diff
Consider using…
PO Vancomycin, Fidoximicin
