covid Flashcards

1
Q

more than ____ viruses cause colds

A

200

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2
Q

what 7 types of covid are there

A

4 = mild illness

3 = serious illness

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3
Q

what are examples of the 3 serious illness

A

SARS or MERS

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4
Q

only ___% cause mild illness>

A

85

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5
Q

what is ACE2 receptor

A

protein found on cells in blood vessels and organs

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6
Q

how does the virus enter the body

A

by ace2 receptor since its airborne

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7
Q

where did covid come from

A

origin unknown but people thunk its created in a lab

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8
Q

what are the 3 key parts from the virus origin?

A

virus from bat, pangolin and unknown origin

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9
Q

how does virus occurring from nature work?

A

2(+) viruses infect same animal at same time and parts of genetic material are exchanged between viruses. then it optimizes itself for survival in a new host

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10
Q

what is wuhan institute of virology

A

covid research

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11
Q

how long does covid last

A

2-6 weeks but symptoms may last longer

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12
Q

symptoms?

A

fatigue, cough, loss of taste/smell, headache, diarrhea, chest, confusionwhat

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13
Q

what can persistence of symptoms cause?

A

hypertension, obesity, mental health conditions

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14
Q

what are gain-of-function experiments

A

try to predict which virus will become deadly

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15
Q

how do they predict which virus will become deadly?

A

creating deadly virus that otherwise wouldn’t exist and try to fix it

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16
Q

first covid gain of function?

A

reported in 1999

17
Q

how is tech in 1999 vs 2019 help with covid?

A

1999:
covid chimeras created in labs
techniques available left traces in genes
could detect genetic manipulation

2019:
covid chimeras created in labs
seamless methods available
could detect genetic manipulation

18
Q

what are effects of ivermectin

A

shows in vitro antiviral activity

19
Q

is ivermectin useful for covid?

A

no can get ivermectin poisoning

20
Q

what is pfizer

A

nirmatrelvir (recent antiviral)

21
Q

what was nirmatrelvir originally made?

A

developed for rhinovirus infections

22
Q

what was operation warp speed

A

puts money for vaccines and hurried to get out of the pandemic

23
Q

more than ___% of population has immunity to virus

A

90

24
Q

2 ways to get covid?

A

get covid, get vaccinated

25
Q

what kills virus

A

antibodies

26
Q

how long does it take to make antibodies

A

several days

27
Q

how are antibodies formed

A

spike protein outside of virus

antibodies bind to spike and that gives immunity to covid

28
Q

what prevents illness

A

immunity

29
Q

pros of viral proteins?

A

established method, highly effective and no risk of infection

30
Q

cons of viral proteins?

A

time consuming to develop (>4 years)
proteins difficult to manufacture
requires a custom made factory for each vaccine

31
Q

what vaccines use mRNA

A

moderna and pfizer

32
Q

what are symptoms of pfizer vaccine at injection and systematic

A

injection: pain, redness and swelling

systematic: fever, fatigue, headache and chills

33
Q

what is higher in vaccine group

A

appendicitis, heart attack and stroke

34
Q

what is higher in placebo group

A

pneumonia, atrial fibrillation and syncope

35
Q

vaccine effect _____ over time?

A

weakens

36
Q

vaccine approval takes ??

A

6-18 months

37
Q

typical vaccine takes _____ years to develop??

A

10

38
Q

moderna took how many days of clinical?

A

took 42 days + 8 months

39
Q

all mRNA vaccines can be made in _______ factory?

A

same