Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

TOP 300 drugs - NAPLEX > Pharmacy foundations > Flashcards

Pharmacy foundations Flashcards

1
Q

Common CYP inhibitors

A

G ❤️ PACMAN
Grapefruit
Protease inhibitors
Azole antifungals
Cyclosporine, Cobicistat
Macrolides (not azithromycin)
Amiodarone (and dronedarone)
Non-DHP CCBs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Common CYP inducers

A

PS PORCS
Phenytoin
Smoking
Phenobarbital
Oxcarbazepine
Rifampin (+ rifabutin, rifapentine)
Carbamazepine
St. Johns Wort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Tyramine-rich food

A

aged cheese, air-dried meats, sauerkraut

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Drugs with additive ototoxicity

A

Aminoglycosides
Cisplatin
Loop diuretics (Esp rapid IV admin)
Salicylates
Vancomycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drugs that are nephrotoxic

A

Anti-infectives: aminoglycosides, amp B, polymyxins, vanco
Cisplatin
CNIs
Loops
NSAIDs
Contrast dye

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drugs that cause immune-mediated hemolytic anemia (positive Coombs test)

A

PCNs & cephalosporins
Isoniazid
Levodopa
Methyldopa
Quinidine
Quinine
Rifampin
Sulfonamides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drugs that increase uric acid

A

Diuretics
Niacin
Low dose aspirin
Pyrazinamide
Cyclosporine, Tacrolimus
Pancreatic enzyme products
Chemotherapy (d/t TLS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drugs to be careful of with TPMT (Thiopurine S-methyltransferase) deficiency

A

Azathioprine
Mercaptopurine
Low doses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Carbamazepine: therapeutic range

A

4-12 mcg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Digoxin: therapeutic range

A

0.8–2 ng/mL (AF)
0.5-0.9 ng/mL (HF)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Gentamicin (traditional dosing): therapeutic range

A

Peak: 5-10 mcg/mL
Trough: < 2 mcg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Lithium: therapeutic range

A

0.6–1.2 mEq/L (up to 1.5 mEq/L for acute symptoms)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Phenytoin/Fosphenytoin: therapeutic range

A

Total: 10-20 mcg/mL
Free: 1-2.5 mcg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Procainamide: therapeutic range

A

4-10 mcg/mL
NAPA (active metabolite): 15–25 mcg/mL
Combined: 10-30 mcg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Theophylline: therapeutic range

A

5-15 mcg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Tobramycin (traditional dosing): therapeutic range

A

Peak: 5-10 mcg/mL
Trough: < 2 mcg/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Valproic acid:therapeutic range

A

50-100 mcg/mL (up to 150 mcg/mL in some patients)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Vancomycin therapeutic range

A

Trough: 15-20 mcg/mL for most serious infections
Trough: 10-15 mcg/mL for less serious (e.g. SSTIs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Orange book (FDA)

A

List of approved drugs that can be interchanged with generics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Pink book (CDC)

A

information on epidemiology & vaccine-preventable diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Red Book, Pharmacy

A

Drug pricing information

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Pink sheet (pharma Intelligence)

A

News report on regulatory, legislative, legal & business developments

21
Q

Purple book (FDA)

A

List of biological drug products, including biosimilars

21
Q

Red Book (AAP)

A

Summaries of pediatric ID, antimicrobial treatment & vaccinations

21
Q

Yellow Book (CDC)

A

Info on health risks of international travel, required vaccinations & ppx medications

22
Q

Green Book (FDA)

A

Information on approved animal drug products

23
Q

Phenylalanine C/I

A

phenylketouria (PKU)

24
Q

Flector (diclofenac patch): admin site & frequency

A

BID to affected areas

25
Q

Daytrana (Methylphenidate): admin site & frequency

A

2 hours prior to school on the hip

26
Q

Exelon (Rivastigmine patch): admin site & frequency

A

Chest, back, upper arm BUT NOT flanks. Once daily

27
Q

Androderm (Testosterone patch): admin site & frequency

A

NOT on scrotum, nightly

28
Q

Lidoderm: admin site & frequency

A

1-3 patches PRN, on for 12 hours, off for 12 hours to affected areas

29
Q

Nitroglycerin patch: frequency

A

on for 12-14 hours, off for 10-12 hours (daily)

30
Q

Duragesic (Fentanyl patch): admin site & frequency

A

Chest, back, upper arms. Q72H

31
Q

Transderm Scop (Scopolamine): admin site & frequency

A

Q72H PRN behind the ear

32
Q

Alora, Vivelle-Dot (Estradiol): admin site & frequency

A

Twice weekly
Ville-dot: lower abdomen or buttock

33
Q

Oxytrol (Oxybutinin patch): admin site & frequency

A

Twice weekly on abdomen, hip or buttock

34
Q

Adlarity (donepezil patch): frequency

A

weekly

35
Q

Catapres-TTS: frequency + pearls

A

Weekly
Contains metal
Comes with its own adhesive

36
Q

Climara (estradiol) patch frequency

A

Weekly

37
Q

Xulane (norelgestromin / ethinyl estradiol): admin site & frequency

A

Weekly on back, abdomen, arm or buttock

38
Q

Patches that contain metal & need to be removed prior to MRI

A

CAN’T
Catapres-TTS
Anderoderm
Neupro(rotigotine)
Transderm Scop

39
Q

Patches that should be flushed after use

A

Daytrana
Duragesic
Butrans
Butrans & duragesic can only be covered with Bioclusive or Tegaderm

40
Q

Promethazine warning

A

Can cause severe tissue injury
Intra-arterial or SC routes should not used.* IM route preferred. *DO not use in < 2 yrs

41
Q

Drugs that have issues with leaching/adsorption/absorption issues with PVC containers

A

LATTIN
Lorazepam
Amiodarone
Taxanes (NOT Abraxane)
Tacrolimus
Insulin
Nitroglycerin

42
Q

Drugs that can only be reconstituted in saline (NO dextrose)

A

Antimicrobials: Ampicillin, Ampicillin/Sulbactam
Daptomycin (Cubicin), Caspofungin (Cancidas), Ertapenem (Invanz)
Infliximab (Remicade)
Phenytoin (Dilantin)

43
Q

Drugs that can only be reconstituted in dextrose (NO saline)

A

Oxaliplatin
Bactrim
Amphotericin B
Synercid (Quinopristin/Dalfopristin)

44
Q

NEVER mix calcium with the following

A

Ceftriaxone LR contains calcium
Phosphate

45
Q

Filter sizes

A

Most: 0.22 micron
Lipids: 1.2 micron

46
Q

Drugs with filter requirements

A

Golimumab
Amphotericin B (lipid formulations)
Lipids
Isavuconazonium
Phenytoin for continuous infusion, not IV push
Amiodarone
Taxanes
Mannitol ≥ 20%
Parenteral nutrition: 1.2 micron

47
Q

Drugs that CANNOT be refrigerated

A

Antimicrobials: Bactrim, Metronidazole, Moxifloxacin
Dexmedetomidine (Precedex)
Phenytoin (Dilantin)
Furosemide (Lasix)
Enoxaparin (Lovenox)

48
Q

Drugs to protect from light

A

PENMD

Phytonadione (Vit. K)
Epoprostenol
Nitroprussde BLUE = cyanide = DONT use
Micafungin
Doxycycline

49
Q

Lovenox Dosing

A

VTE ppx: 40mg SC daily or 30mg SC BID (If CrCl <30, then 30mg SC daily)
VTE treatment: 1mg/kg SC Q12H or 1.5mg/kg daily (If CrCl < 30, then 1 mg/kg/day)

50
Q
A

TOP 300 drugs - NAPLEX (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions