151-200 MOA

Question 1

Diflucan/Fluconzazole

Answer 1

Interferes with fungal cytochrome P450 activity which decreases ergosterol synthesis and inhibits the cell membrane formation

Question 2

Flagyl/Metronidazole

Answer 2

Interacts with DNA to cause loss of helical DNA structure and strand breakage resulting in protein synthesis inhibition and cell death in susceptible organisms

Question 3

Gentamicin/Tobramycin

Answer 3

Aminoglycosides

Question 4

Cephlexin/Keflex
Cefazolin/Kefzol

Answer 4

First Generation Cephalosporin
Inhibit bacterial cell wall synthesis via Penicillin-binding proteins

Question 5

Lamisil/Tebrinafine

Answer 5

Sythetic allylamine derivative that inhibits squalene epoxidase, inhibiting the sterol biosynthesis causing a deficiency in ergosterol in the cell membrane leading to fungal dealth

Question 6

Levaquin/Levofloxacin

Answer 6

Fluoroquinolone
Inhibits the DNA-gyrase in bacteria, causing the supercoiled DNA to promote breakage DNA strands

Question 7

Macrobid/Macrodantin
Nitrofurantoin

Answer 7

Inhibits the bacterial ribosomal protein leading to the inhibition of protein synthesis, aerobic energy, DNA, RNA, and cell wall synthesis

Question 8

Meropenem/Merrem

Answer 8

Inhibits the bacterial cell wall synthesis by binding to several of the penicillin-binding proteins which then inhibit the final transpepidation step of peptidoglycan synthesis bacterial cell walls

Question 9

Fosfomycin/Monurol

Answer 9

Phosphonic acid derivative that inhibits the bacterial cell wall by inactivating pyruvyl transferase, which is critical in the synthesis of cell wall of bacteria

Question 10

Moxifloxacin

Answer 10

DNA gyrase inhibitor and topoisomerase inhibitor

Question 11

Nafcillin

Answer 11

Interferes with bacterial cell wall synthesis during active multiplication, cause cell wall destruction

Question 12

Nystatin

Answer 12

Binds to sterols in fungal cell membrane

Question 13

Cefdinir/Omnicef

Answer 13

Inhibit bacterial cell wall synthesis by binding to one or more penicillin-binding proteins which inhibits the final transpeptidation step of peptidoglycan synthesis in the cell wall

Question 14

Rocephin/Ceftriaxone

Answer 14

Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin binding proteins, which inhibits the final transpepidation step of peptidoglycan synthesis of bacterial cell walls