BIOL301 class 18

Question 1

pyruvate dehydrogenase complex (PDC)

Answer 1

• pyruvate is transported into the mitochondrial matrix and acetyl co-a and NADH’s are produced
• pyruvate entering the mitochondria can be carboxylated to OAA or decarboxylated to Acetyl-CoA depending on the need for each

Question 2

FA Synthesis occurs in cytosol

Answer 2

• requires NADPH which comes from the cytosol
• only lipogenic tissues like the liver and adipocytes express fatty acid synthase