nervous Flashcards

1
Q

what’s in the PNS?

A

The portion of nervous system outside CNS
consists mainly of nerves that extend from brain and spinal cord
1) Spinal nerves to and from spinal cord
2) Cranial nerves to and from brain

cranial nerves, spinal nerves, ganglia

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2
Q

what is motor output?

A

is the conduction of signals from integration centers to effector cells.
- Effector cells carry out the body’s response to a stimulus

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3
Q

what center is open for integration?

A

CNS

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4
Q

how are impulses conducted along a nerve?

A

Dendrite  cell body  axon hillock  axon

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5
Q

what does the myelin sheath cover?

A

axon

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6
Q

where are the neurotransmitters stored?

A

Axon endings are called synaptic terminals: they contain neurotransmitters which conduct a signal across a synapse

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7
Q

whats a reflex arc?

A

The reflex arc is a simple nerve circuit. A reflex is an autonomic response.

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8
Q

whats the knee reflex called?

A

patellar

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9
Q

what does a reflex check?

A

A reflex checks the health of the nervous tissue between the periphery and the spinal cord

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10
Q

what are roots?

A

There are bundles of axons, called roots which connect the spinal nerves to the spinal cord

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11
Q

what are the two types of roots?

A

The posterior ones (dorsal) are groups of sensory axons, which conduct nerve impulses from peripheral sensory receptors (such as those in the skin) to the CNS.

The anterior ones (ventral) are groups of motor neurons, which carry mesages from the CNS to the effectors, which could be muscles or glands.

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12
Q

whats a ganglion?

A

A ganglion is a cluster of nerve cell bodies within the PNS

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13
Q

whats a nucleus?

A

A nucleus is a cluster of nerve cell bodies within the CNS.

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14
Q

what are meninges and what are the different layers?

A

Meninges: are layers of connective tissues which cover the brain and spinal cord.

Moving from outside towards the brain or spinal cord these layers are
1) the dura mater
2) the arachnoid mater
3) the pia mater

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15
Q

how do dorsal and ventral roots link?

A

As the spinal nerve nears the spinal cord, it splits into dorsal and ventral roots. The dorsal root contains only the axons of sensory neurons, whereas the ventral roots contain only the axons of the motor neurons.

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16
Q

what are the different glia supporting cells and where are they found?

A

Astrocytes are found within the CNS. They provide structural and metabolic support
2. Oligodendrocytes are found within the CNS.
Form a myelin sheath by insulating axons.
3. Schwann cells are found within the PNS.
Form a myelin sheath by insulating axons.

  1. Ependymal cells: Cilia beat to circulate CSF
17
Q

what do astrocytes do?

A

By inducing the formation of tight junctions between capillary cells astrocytes help form the blood-brain barrier.
Like neurons, astrocytes communicate with one another via chemical signals.

18
Q

wat do oligodendrocytes and Schwann cells do?

A

Form a myelin sheath by insulating axons.

19
Q

what do ependymal cells do?

A

Cilia beat to circulate CSF
- Line the central cavities of the brain and spinal column
- Form permeable barrier between cerebrospinal fluid (CSF) in cavities and tissue fluid bathing CNS cells

20
Q

where are anions and cations more concentrated?

A

Anions are more concentrated within a cell.
Cations are more concentrated in the extracellular fluid

21
Q

what are the two types of gated ion channels?

A

chemically gated and voltage gated

22
Q

what are the cations?

A

K+ the principal intracellular cation.
Na+ is the principal extracellular cation.

23
Q

what are the anions?

A

Proteins, amino acids, sulfate, and phosphate are the principal intracellular anions.
Cl– is principal extracellular anion.

24
Q

what do ungated channels do?

A

allow ions to diffuse across the plasma membrane.
These channels are always open.
This diffusion does not achieve an equilibrium since sodium-potassium pump transports these ions against their concentration gradients.

25
Q

what are the types of gated ion channels?

A

1) Chemically-gated ion channels open or close in response to a chemical stimulus (ex neurotransmitter)
2) Voltage-gated ion channels open or close in response to a change in membrane potential.
Hyperpolarization: Gated K+ channels open so K+ diffuses out of the cell and so the membrane potential becomes more negative.
Depolarization: Gated Na+ channels open so Na+ diffuses into the cell and the membrane potential becomes less negative.

3) Mechanically gated channels: Open and close in response to physical deformation of receptors, as in sensory receptors

26
Q

true or false, the Na K pump works to create a gradient, to then allow the gated channels to open and make action potentials

A

true

27
Q

what are the two gates of the voltage gated Na+ Chanel?

A
  1. Closed activation gates open rapidly in response to depolarization. The opening of the activation gates allows sodium ions INTO the cell leading to a greater depolarization.
  2. Open inactivation gates close slowly in response to threshold depolarization. This prevents any further sodium ions from entering the cell.
28
Q

what happens during the undershoot?

A

During the undershoot both the Na+ channel’s activation and inactivation gates are closed.

29
Q

what is saltatory conduction?

A

In myelinated neurons only unmyelinated regions of the axon depolarize. The action potential jumps from one node of Ranvier to the next. This is called saltatory conduction

node of ranvier is depolarized region

30
Q

describe both type of synapses?

A

Electrical Synapses.
Action potentials travels directly from the presynaptic to the postsynaptic cells via gap junctions.
Chemical Synapses.
More common than electrical synapses.
Postsynaptic chemically-gated channels exist for ions such as Na+, K+, and Cl-.
Depending on which gates open the postsynaptic neuron can depolarize or hyperpolarize.

31
Q

how does a neurotransmitter get released?

A

An action potential arrives at the pre-synaptic membrane and causes the neurotransmitter containing vesicles to fuse with the pre-synaptic membrane. The neurotransmitter will be released into the synaptic cleft, will bind to the ion channel on the post-synaptic membrane and cause changes in the ion channels of the post-synaptic membrane

32
Q

what’s the enteric nervous system?

A

the digestive system is endowed with its own, local nervous system referred to as the enteric or intrinsic nervous system. The magnitude and complexity of the enteric nervous system is immense - it contains as many neurons as the spinal cord.

33
Q

what are the three brain regions?

A

forebrain: hypothalamus, cerebrum
midbrain
hindbrain (pons and medulla)

34
Q
A