NEISSERIA SPECIES and MORAXELLA CATARRHALIS

Question 1

acute pyogenic infection, primarily in urethra, endocervix, anal canal, pharynx and conjunctiva. gonorrhea -“flow of seed”- urethral discharge was mistaken for semen.

Answer 1

Neisseria gonorrhoeae

Question 2

Neisseria gonorrhoeae -“Venereal Disease”

Answer 2

Sexually Transmitted Infection

Question 3

3 Outer Membrane proteins of Neisseria Gonorrhoeae

Answer 3

Protein I (porB)
Protein II (Opa)
Protein III (Rmp)

Question 4

An outer membrane proteins that is protective against inflammation.

Answer 4

Protein I (porB)

Question 5

An outer membrane protein that is adherence to phagocytic cells and EC.

Answer 5

Protein II (Opa)

Question 6

An outer membrane protein that is reduction modified protein- blocks host serum IgG.

Answer 6

Protein III (Rmp)

Question 7

attachment to host tissues present in types T1 T2 T3,T4,T5 (avirulent) -no pili

Answer 7

Pili — Neisseria gonorrhoeae

Question 8

protect against phagocytosis.

Answer 8

capsule — Neisseria gonorrhoeae

Question 9

Most commonly acquired by sexual contact from asymptomatic carrier (primary reservoir)

Answer 9

Epidemiology — Neisseria gonorrhoeae

Question 10

HPV, C. trachomatis, N. gonorrhoeae

Answer 10

Epidemiology — Neisseria gonorrhoeae

Question 11

(males )- purulent discharge and dysuria and
cervicitis (female)

Answer 11

Urethritis - Clinical Infections of Neisseria gonorrhoeae

Question 12

(auxotypes) AHU strains ( require arginine, hypoxanthine, uracil)

Answer 12

Asymptomatic men - Clinical Infections of Neisseria gonorrhoeae

Question 13

PID, sterility, ectopic pregnancy and perihepatitis (Fitz-HughCurtis syndrome)

Answer 13

Clinical Infections - Neisseria gonorrhoeae

Question 14

Conjunctivitis (Ophthalmia neonatorum)

Answer 14

Clinical Infections - Neisseria gonorrhoeae

Question 15

“gonorrhoeae” means

Answer 15

flow of seed

Question 16

Primary sources are oral secretion/ respiratory droplets (close contact).

Answer 16

Clinical Infections - Neisseria Meningitidis

Question 17

Abrupt onset of frontal headache, stiff neck, fever.

Answer 17

Clinical Infections - Neisseria Meningitidis

Question 18

Release of toxins in the blood that breakdown the walls of the blood vessels.

Answer 18

Meningococcemia - Clinical Infections of Neisseria Meningitidis

Question 19

hemorrhaging of blood into skin & mucous membranes

Answer 19

Purpura(bruises) and Petechial rash(red spot) — clinical infections of Neisseria Meningitidis

Question 20

“Purpura” means

Answer 20

bruises

Question 21

“Petechial rash” means

Answer 21

red spot

Question 22

Disseminated intravascular coagulation (DIC) (normal coagulation is disrupted and abnormal bleeding occurs), septic shock, hemorrhage of adrenal glands (Waterhouse-Friderichsen syndrome)

Answer 22

Meningococcemia - clinical infections of Neisseria Meningitidis

Question 23

Attachment to respiratory epithelial cell.

Answer 23

virulence factor of Moraxella catarrhalis

Question 24

Commensal of the upper respiratory tract.

Answer 24

epidemiology — Moraxella Catarrhalis

Question 25

Localized infections (otitis media and sinusitis)

Answer 25

clinical infections — Moraxella catarrhalis

Question 26

Lower respiratory tract infections

Answer 26

clinical infections — Moraxella catarrhalis

Question 27

Systemic infections (endocarditis, meningitis, etc

Answer 27

clinical infections — Moraxella catarrhalis

Question 28

Glucose positive (yellow); all other are negative (red)

Answer 28

Neisseria gonorrhoeae

Question 29

Glucose and maltose positive (yellow); all
other are negative (red

Answer 29

Neisseria meningitidis

Question 30

all tubes negative (red

Answer 30

Moraxella catarrhalis

Question 31

small, tan, translucent and raised

Answer 31

colony morphology — N. gonorrhoeae

Question 32

small, tan, may be mucoid and convex

Answer 32

colony morphology — N. meningitidis

Question 33

Smooth, opaque, gray to white colony may be wept intact (hockey puck), 48-hr colony - Wagon wheel

Answer 33

colony morphology — M. catarrhalis

Question 34

Positive to Superoxol test- 30% H2O2

Answer 34

N. gonorrhoeae