membrane transport ✅ Flashcards

1
Q

In a phospholipid what is polar and non-polar

A

polar - phosphate head
non-polar - fatty acid tail

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what do phospjolipds consist of

A

a molecule of glycerol two fatty acid tail and a phosphate group

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What way do the hydrophobic tails face and head

A

inwards - tails
outwards - heads

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

why can large molecules not pass through the bilayer

A

because the hydrophobic region is tightly packed and has low permeability to larger molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

why can polar molecules not pass through the lipid bilayer

A

polar molecules and ions through the hydrophobic tails because they have a hydrophilic nature which means they will not interact with hydrophobic fatty acids
tails

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the function of the phospholipid bilayer

A

provides a barrier to the movement of substances in and out of the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

3 factors of Integral proteins

A

• amphipathic
• embedded in phospholipids bilayer
• can be embedded across both /one layer of

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What type of membrane proteins

A

integral
peripheral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

3 factors of peripheral proteins

A

• hydrophilic
• attached either to surface of integral proteins
• inside or outside the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the 4 functions of membrane proteins

A

Transport
Receptors
Immobilised enzymes
Cell adhesion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the function of transport proteins

A

allow ions and polar molecules to travel across membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the two types of transport proteins

A

Channel and carrier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Explain channel proteins

A

these form holes/pores through which molecules can travel through

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Explain carrier proteins

A

undergo conformationa change to transport substances across a membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Transport proteins

A

allow the cell to control which substances enter or leave

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the receptors used for

A

binding of peptide hormones
the binding generates a signal that triggers a series of reactions inside the cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are immobilised enzymes

A

They are integral proteins with the active site exposed on the surface of the membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What happens in cell adhesion

A

allows cells to attach to neighbouring cells within a tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is the purpose of glycoproteins in cell-to cell recognition

A

act as markers or antigens

20
Q

In simple diffusion what way do the molecules move

A

down the conc gradient (high to low)

21
Q

Example of simple diffusion in oxygen

A

oxygen diffuse into cells from capillaries

22
Q

Example of simple diffusion in c02

A

carbon dioxide diffuses out of cells and into capillaries

23
Q

What are the 3 factors that affect the way substances move across the membrane

A
  • steepness of conc gradient
  • temp
  • surface area
24
Q

Explain how the steepness in conc gradient affects the rate at which substances move across membrane

A
  • the greater the diff in conc across a membrane , the higher the rate of diffusion
25
Q

Explain how the temperature affects the rate at which substances move across membrane

A

the higher the temp the higher the rate of diffusion
(molecules have more kinetic energy move faster)

26
Q

Explain how the surface area affects the rate at which substances move across membrane

A

the greater the surface area the higher rate of diffusion

27
Q

What is the diffusion like in large molecules

A

they diffuse more slowly (require more energy to move )

28
Q

what is the diffusion like in uncharged molecules

A

diffuses faster as they move directly across the phospholipid bilayer

29
Q

explain the diffusion of non-polar

A

diffuse more quickly as they are soluble in non-polar phospholipid bilayer

30
Q

Define osmosis

A

the diffusion of water molecules from a dilute solution (high water potential) to a more concentrated solution (low water potential) across a partially permeable membrane (down conc gradient )

31
Q

what are aqua porins

A

channel proteins that allow water to pass through membranes more freely

32
Q

Facilitated diffusion is used for substances that cannot pass through the phospholipid bilayer

A

large molecules
polar molecules
ions

33
Q

what does facilitated diffusion involve

A

transport proteins
down a conc gradient
no energy required (passive )

34
Q

explain the process of a carrier proteins

A

the substance to be transported attaches to a binding site causing a conformational change in the carrier protein

35
Q

define active transport

A

the movement of molecules and ions across a cell membrane from a region of lower concentration to higher concentration (against )

36
Q

what are the factors do active a transport

A

• against conc gradient
• requires energy from respiration
• requires carrier proteins

37
Q

What is the role of ATP in action transport

A

ATp provides energy (produced during respiration) which allows carrier proteins to change shape
ATP hydrolysed to release energy

38
Q

define selective permeability

A

the ability of the membrane to differentiate between different types of molecules only allowing some molecules through by blocking others

39
Q

what is simple diffusion dependent on

A

size
hydrophilic/ hydrophobic nature of molecules

40
Q

what are glycoproteins

A

cell membrane proteins that have a carbohydrate chain attached on the extra cellular side

41
Q

What are glycolipids

A

lipids with carbohydrate chains attached

42
Q

What are the functions of glycoproteins/lipds

A

• The carb chain enables them to act as receptor molecules which allows them to bind with substances at the cell surface

43
Q

Why is the cell membrane described as “fluid”

A

the phospholipids and proteins can move around within their own layers

44
Q

why are cell membranes described as mosaics

A

because the scattered pattern produced by the proteins within the bilayer looks like a mosaic (from above )

45
Q

What does the fluid mosaic model involve

A

phospholipids
cholesterol
glycoproteins/lipds
integral and peripheral proteins