Immunology Flashcards
What type of hypersensitivity is allergy?
Type 1
What type of hypersensitivity is IgG or IgM against antigens presented on the surface of cells?
Type 2
What type of hypersensitivity is Immune complexes against antigens?
Type 3
What type of hypersensitivity is T-cell mediated against antigens (delayed)?
Type 4
What is the difference between a primary and secondary immune deficiency?
Primary = congenital defect in the immune system
Secondary = consequence of a condition, toxin or drug
Name the conditions caused by B cell deficiency
Primary Antibody deficiency
X-linked agammaglobulinemia (Bruton’s Disease)
Hyper-IgM syndromes
Common Variable Immunodeficiency Disorders
Selective IgA Deficiency
Name the conditions caused by T cell deficiencies
AIRE mutation
Wiskott-Aldrich syndrome
DiGeorge Syndrome
Ataxia Telangiectasia (Louis-Bar Syndrome)
Name the condition caused by a mixed B and T cell deficiency
Severe combined immunodeficiency (SCID)
Name the innate immune deficiencies
Macrophage deficiency
IRAK-4 deficiency
Defect in Neutrophil Function
Chronic Granulomatosis Disease (CGD)
Complement Deficiencies
What is the function of a plasma B cell?
secrete antibodies (also called immunoglobulins)
Which cell type recognises MHCI?
CD8 (cytotoxic t cells)
Which cell type recognises MHCII?
CD4 (helper T cells)
