Chapter 49 Flashcards

1
Q

Inflammation means what has happened to the body

A

Injury

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2
Q

What 4 things do NSAIDs do

A

Analgesia
Anti inflammatory
Anti pyretic
Anti platelet (aspirin)

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3
Q

What med class is the first line treatment for gout and hyperuricemia

A

NSAIDS

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4
Q

What is the main side effect of NSAIDs

A

Bleeding

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5
Q

Which NSAID is a salicylate

A

Aspirin

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6
Q

Which NSAIDs are acetic acid derivatives

A

Diclofenac sodium
Indomethacin sulindac
Ketorolac

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7
Q

Which NSAID is a COX2 inhibitor

A

Celecoxib

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8
Q

Which NSAIDs are propionic acid derivatives

A

Ibuprofen
Naproxen

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9
Q

Which NSAID is given to close the opening between the aorta and pulmonary artery in newborns

A

Ibuprofen

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10
Q

Which NSAID should be given if MI is suspected

A

Aspirin

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11
Q

What do NSAIDs do

A

Block the inflammatory response

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12
Q

Which NSAID is the only anti platelet one

A

Aspirin

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13
Q

When should NSAIDs not be given

A

Bleeding
Vitamin K deficiency
Peptic ulcer disease

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14
Q

Why should someone with rhinitis not be given an NSAID

A

The nose is highly vascular. BLEEDING

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15
Q

After what gestation should pregnant women stop taking NSAIDs

A

32 weeks to prevent bleeding during labour

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16
Q

How should NSAIDs be administered to prevent GI bleed

A

Give with food or milk

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17
Q

NSAIDs become ulcerogenic when given with which drug

A

Corticosteroids. DO NOT GIVE

18
Q

What is a sign of aspirin toxicity

A

Ringing in ears

19
Q

Which med is given to patients on NSAIDs to prevent GI bleed

A

Misoprostol

20
Q

Why can misoprostol not be given to pregnant women

A

Induces contractions

21
Q

Why can aspirin not be given to someone under 18

A

Rye’s syndrome

22
Q

Which NSAID is used for thromboprevention and what is typical dose

A

Aspirin, 81mg

23
Q

Which NSAID besides ibuprofen can be used to close opening in newborn heart

A

Indomethacin

24
Q

Which NSAID has analgesic effects similar to narcotics

A

Ketorolac

25
Q

Which NSAID can only be used for 5-7 days due to GI and kidney damage with prolonged use

A

Ketorolac

26
Q

Doses more than what per day from ibuprofen increase risk of stroke and MI

A

2400mg

27
Q

When taking ibuprofen which organ needs to be monitored

A

Kidney

28
Q

How long does it take for ibuprofen to have anti inflammatory effects

A

Up to 7 days

29
Q

Which NSAID cannot be given with a sulfa allergy

A

Celecoxib

30
Q

What adverse effect can NSAIDs cause on the heart

A

Pulmonary edema that is not caused from the heart

31
Q

NSAIDs interact with

A

Anything that will increase bleeding

32
Q

What causes gout

A

Underexcretion of uric acid
Overproduction of uric acid

33
Q

What foods need to be eliminated for gout patients

A

Foods containing purine

34
Q

What foods contain purine

A

Seafood
Organ
Yeast
Beer
Wine
Beans
Peas
Oatmeal
Lentils
Spinach
Asparagus
Cauliflower
Mushrooms

35
Q

What do antigout drugs do

A

Control symptoms and prevent attacks

36
Q

Probenecid prolongs the effects of which drug

A

Penicillin

37
Q

Which antigout drug can cause Steven Johnson syndrome

A

Allopurinol

38
Q

Which antigout med prevents tumor lysis from releasing more uric acid into blood

A

Allopurinol

39
Q

Which antigout drug can be used prophylactically in acute attacks

A

Colchicine

40
Q

Which herbal products can be used for anti inflammatory

A

Glucosamine and Chondroitin