Specific Population Groups Flashcards

Pregnancy

1
Q

The most important indicator of a healthy baby is a:

A

healthy mother

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2
Q

Who are the specific population groups?

A

Pregnant women, older adults, children

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3
Q

What important risk factor during pregnancy should be addressed?

A

Important factors linked to drugs

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4
Q

Birth defects involving the malformation of the fetus of fetal organs.

A

Teratogenesis

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5
Q

Most psychotropic drugs flow through the

A

blood brain barrier

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6
Q

Examples of teratogenesis

A

Spina bifida or cleft spine, facial deformity, cleft palate

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7
Q

Drugs that produce malformations to fetus.

A

Teratogens

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8
Q

Learning difficulties, developmental delays, poor neonatal adaptation (residual effects on the newborn that can include symptoms as hypothermia, difficulties with eating and sleeping, tachycardia and irritability)

A

Behavioral Teratogenesis

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9
Q

With some exceptions, psychiatric medications generally fall into

A

FDA category C

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10
Q

Is a common phenomenon during pregnancy between 10-15 percent of pregnant women.

A

Depression

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11
Q

Is the most prevalent complicating event, occuring in about 15 percent of women.

A

Postpartum depression

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12
Q

Is significantly associated with poor pregnancy outcomes.

A

Untreated or unrecognized depression

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13
Q

What do people with depression, postpartum depression, and untreated depression take?

A

Antidepressants

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14
Q

When an offspring has teratogenesis, the mother may have:

A

taken drugs during pregnancy, whether prescribed or for recreational use. Some food may also contain teratogens, and the mother may or may not be aware of it.

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15
Q

Is the best initial step for addressing mild to moderate depression during pregnancy.

A

Psychotherapy

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16
Q

Teratogenesis is not manifested from genetics in nature but from:

A

environmental factors (teratogens)

17
Q

Is the best approach to begin with antidepressant and other psychotropic medications.

A

Conducting a thorough history

18
Q

What should we do if the risk of relapse is high?

A

Warrant the use of medication, discussing pros and cons with the pregnant woman

19
Q

Warranting the use of medication, discussing pros and cons with the woman is

A

Imperative

20
Q

What is the goal of medication management?

A

Establish and maintain a euthymic state throughout the duration of pregnancy- utilizing the lowest possible effective medication dosing strategies.

21
Q

What is a risky proposition during pregnancy?

A

Use of multiple medications

22
Q

Potential fetal risk, cannot be ruled out.

A

FDA Category C

23
Q

What is under FDA Category C?

A

Antidepressant, antipsychotics

24
Q

TRUE OR FALSE: SSRIs and Cylics are not associated with teratogenesis

A

True

25
Q

TRUE OR FALSE: 25 percent of children with third trimester exposure to SSRIs showed withdrawal: lack of crying, increased muscle tone, irritability and poor sleep.

A

FALSE (30 percent)

26
Q

If physical teratogenesis is not manifested, there may be a ———– teratogenesis manifested instead.

A

Behavioral

27
Q

T-F: MAOIs are not studied extensively; nursing is generally contraindicated for women taking these drugs

A

TRUE

28
Q

What is generally not recommended during pregnancy?

A

Lithium

29
Q

Why is Lithium not recommended during pregnancy?

A

it is linked to neonatal effects, including respiration and EKG and heartrate abnormalities, fetal cardiac irregularities

30
Q

What agent that has been mostly studied and is not linked to congenital malformations during the first trimester?

A

Haldol (Haloperidol)

31
Q

What risk does second-generation antipsychotics carry?

A

metabolic syndrome

32
Q

The use of this class of drugs should be avoided during the first trimester of pregnancy.

A

Benzodiazepines

33
Q

What is the risk of benzodiazepines?`

A

Orofacial clefts, neonatal CNS depression and withdrawal symptoms.

34
Q

Most of these drugs are established teratogens especially Tegretol (carbamazepine), and Depakote (divalproex sodium) and should be avoided during pregnancy.

A

Anticonvulsants

35
Q

When these anticonvulsants are used during pregnancy, these does not increase the risk of major birth malformations.

A

Lamictal (lamotigrine), Trileptal (oxcarbazepine), and Neurontin (gabapentin)