Lecture 19: Memory and the Hippocampus

Question 1

Pattern Completion

Answer 1

Reinstatement of a memory from a partial cue (something reminding you of something else)

Question 2

Two-stage model for memory formation in the hippocampal-cortical circuit

Answer 2

1. Sensory experience gets encoded and reaches the cortex
2. Cortex sends info to hippocampus
3. Hippocampus stores it for a little while (hours, days) (encoding)
4. Information propagates from the hippocampus to the cortex during sleep
   - Memory representation is no longer in the hippocampus, it is stored in the cortex

Question 2

Hippocampal Replay

Answer 2

• A time-compressed reoccurrence of the same sequence of place-cell firing as during recent behavior
• Also happens during sleep to put memory into cortex
• Supports learning