histology of the thyroid, parathyroid and pancreas SDL

Question 1

Answer 1

pale pink: thyroglobulin within follicles
purple: simple cuboidal epithelium

Question 2

what is the red staining

Answer 2

red blood cells

Question 3

discuss how thyroglobulin is made

Answer 3

• Synthesis of thyroglobulin in follicular epithelial cells – secreted to follicles
• Resorption, diffusion, oxidation of iodide – follicular epithelial cells active transport iodide into cytoplasm from bloodstream catalyzed by thyroid peroxidase
• Iodination of thyroglobulin in the colloid
• Formation of T3 and T4 by oxidative coupling reactions – t3 or t4 stays linked to thyroglobulin and stored in colloid
• Resoroption of colloid – thyroglobulin degraded, leaving free t4, t3, dit mit
• Release od t4 and t3 to circulation

Epithelial cells only t4, most t3 actually comes from conversion of t4 elsewhere in the body

Question 4

which side of the image is thyroid and which is parathyroid

Answer 4

right side: thyroid
left side: parathyroid

Question 5

Answer 5

C= thyroid parafollicular C cells = calcitonin

Question 6

label pancreas

Answer 6