Inflammatory/immune-mediated Flashcards

1
Q

Investigations for Myasthenia Gravis

A

CK (normal)
CT thorax (thymus!!)
single fibre electromyography

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2
Q

Pathogenesis of Myasthenia Gravis

A

Autoantibodies against acetylcholine receptors

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3
Q

why is the thymus relevant in MG

A

15% thymoma
50-70% thymic hyperplasia

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4
Q

Management for MG (not in crisis)

A

long acting acetylcholinesterase inhibitors (pyridostigmine)

might require immunosupression

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5
Q

Management of Myasthenic crisis

A

Plasmapheresis
IV Igs

No steroids (can acutely worsen)

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6
Q

GBS diagnostics investigations

A

LP- raised protein
Nerve conduction studies

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7
Q

GBS picture with ophthalmoplegia

spot diagnosis

A

miller fisher syndrome

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