Chancroid Flashcards

1
Q

Definition

A

STI caused by bacterium HAEMOPHILUS DUCREYI
- Bacteria invade the epithelium of the gential region, resulting in inflammation, necrosis and ulceration.

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2
Q

Epidemiology

A
  • Rare in the UK and MC in Africa and SE Asia
  • Unprotected sexual intercourse
  • Multiple sexual partners
  • Men are affected more often than women
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3
Q

Signs

A
  • Painful ulceration
  • Solitary ulcers on the penis or vulva
  • Tender unilateral inguinal lymphadenopathy: fluctuant lymphadenitis (bubo formation)
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4
Q

Symptoms

A
  • Genital pain
  • Genital ulcer
  • Painful groin swelling
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5
Q

Diagnosis

A
  • Swab of ulcer base: PCR testing for H.ducreyi
  • HIV serology: co-infection common
  • Treponema pallidum particle agglutination (TPPA), treponemal enzyme immunoassay (EIA)

Consider doing:
- Bubo aspirates: fluid may be collected from fluctuant buboes

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6
Q

Treatment

A

FIRST LINE:
- ABx: single dose azithromycin (macrolide)
= If CI ceftriaxone, erythromycin or ciprofloxacin
- Partner notification and treatment: sexual contacts within the preceding 3 weeks
SECOND LINE:
- Abscess drainage: if buboes (swollen lymph nodes) are fluctuant, needle aspiration can provide symptomatic relief.

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7
Q

Complications

A
  • Genital scarring and stricture
  • Abscess formation in inguinal lymph nodes (buboes)
  • Spread of the infection to other areas of the body: rare but can be severe.
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