Readings Flashcards
1
Q
FHM
A
- 1-3 day migraine
- Headache + vomiting
- Pore-forming Ca region mutation = hemiplegic migraine w progressive cerebellar ataxia
2
Q
EA2
A
- Ataxia, maybe: vertigo, nausea & headaches
- Brought on by emo-stress, exercise & alcohol
- Ca chans = truncated @ diff sites`
3
Q
CSNB
A
- X-linked recessive
- Night blind, myopia, nystagmus & strabismus
- Rods = disfunctional
- Ca chans = truncated
4
Q
Generalized Epilespy w Febrile Seizures
A
- Infancy –> early puberty
- -Chrom2 mutation encodes alpha subunit
- -Chrom19 mutation slows Na activation
5
Q
Benign Familial Neonatal Convulsion
A
-Mutation in 2 diff genes = K chan mutation = convulsions/ brief seizures from 1st week –> few months
6
Q
EA1
A
- Defect in VGK chan = brief ataxia episodes
- Defect of diff VGK chan inhibits fcn of normal ones
7
Q
Pupillary Light Reflex
A
Pretectum –> Pretectal Neurons sent –> Edinger Westphal Nucleus –> Preganglionic Parasympathetic Neurons terminate on –> neur of Ciliary Ganglion (via Cranial Nerve 3) = constrictor muscles of iris
8
Q
Hubel & Wiesel
A
- Cat
- Processing in Visual System
9
Q
Hodgkin, Huxley & Eccles
A
- Ions behind IPSP & EPSP
- Voltage Clamp Technique
10
Q
Neher & Sakmann
A
- Single ion channel function
- Patch-clamp
11
Q
Shimomura, Chalfie & Tsien
A
-Green fluorescent protein - GFP
