(17) GGT - LIVER ENZYMES Flashcards

1
Q

Action: Catalyze the transfer of the γ-glutamyl residue from γ-glutamyl peptides to amino acids, H20, etc.

A

GGT ( gamma-glutamyl transferase )

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2
Q

Most common donor γ-glutamyl peptide

A

glutathione

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3
Q

NOTE:

Diagnostic significance of GGT

A

o dx of hepatobiliary disorders & chronic alcoholism
o sensitive marker for ethanol intoxication
o marker for occult alcoholism

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4
Q

o Szaz Assay

▪ Absorbance of p-Nitroaniline is measured @ 405-420nm
* Product has color:

A

Assay for Enzyme Activity for GGT

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