18. Absorbtion and circulation of lipids, lipolysis, lipogenesis Flashcards
18. Absorbtion and circulation of lipids in the organism. Lipolysis. Steps, location, regulation, importance. Lipogenesis. Steps, location, regulation, importance.
Why is lipids in the organism important?
-Storage form of energy -Adipose tissue and the liver are important pools of lipids. -For isolation and heat -Support internal organs -It is important for the resorption of fat soluble vitamins -Essential nutritional factors (linoleic acid)
Where is the lipids absorped?
in the intestine, bile emulsification and with pancreatic lipase.
How does the lipids move?
-They are stored in adipose tissue as triacylglycerols, it is a fuel storage. The mobilization is initiated by the hormone sensitive lipase enzyme, it removes the FA. -Free FA can move through the membranes and connect to albumin and continue to tissue.
Lipolysis:
Circulation of lipids:
After absorption bu the intestinal mucosa cells, resynthesis of triacylglycerols happen. Packed VLDL form a complex with chylomicrons in the plasma with cholesterol ester and then to the lymph to different tissues.
Lipogenesis:
Location of lipogenesis and lipolysis:
Liver (storage), enterocytes
