18.6-18.9 Flashcards
(26 cards)
Pituitary gland (hypophysis)
The master endocrine gland that controls other glands. Pea shaped structure that lies in hypophyseal fossa and has two regions: anterior and posterior pituitary.
Hypothalamus
Controls the pituitary gland. Major link between nervous and endocrine system. Synthesizes 9 different hormones.
Infundibulum
Funnel. Composed of anterior and posterior pituitary.
anterior pituitary
75% of pituitary weight.
Secretes hormones to regulate growth and reproduction.
Composed of epithelial tissue.
composed of two parts:
1) pars distalis
2) pars tuberalis
Pars tuberalis
Part of anterior pituitary. Forms sheath around infundibulum.
Posterior pituitary
Composed of neural tissue. Consists of two parts.
1) pars nervosa
2) pars intermedia
Hypophyseal portal system flow of order
Superior arteries>primary plexus>veins>secondary plexus
Neurosecretory cells
Synthesize the hypothalamic releasing and inhibiting hormones
Tropic hormones (tropins)
Anterior pituitary hormones that act on other endocrine glands
Hormones of the anterior pituitary:
Somatotrophs Thyrotrophs Gonadotropins Lactotrophs Corticotrophs
Somatotrophs
Secrete HGH, Aka somatotropin. Which then stimulates release of insulin growth factors (iGF)
Thyrotrophs
Thyroid stimulating hormone, aka thyrotropin.
Gonadotrophs
Aka gonadotropins, 2 kinds-
1) follicle stimulating hormone (FSH)
2) luteinizing hormone (LH)
Produce estrogen in ovaries and testosterone in testes.
Lactotrophs
Secrete prolactin (PRL) which starts milk production in mammary glands.
Corticotrophs
Secrete adrenocorticotropic hormone (ACTH) aka corticotropin . Stimulates secretion on cortisol or melanocyte-stimulating hormone (MSH).
Functions of IGF
1) increase uptake of amino acids accelerating protein synthesis
2) enhance lipolysis
3) increase carb metabolism by decreasing glucose uptake
Hypoglycemia
Low blood glucose concentration
Hyperglycemia
High blood glucose concentration , stimulates hypothalamus to secrete GHRH
Posterior pituitary
Does not synthesize hormones, but stores and releases two hormones: oxytocin (OT) & antidiuretic hormone (ADH)
Blood flow of posterior pituitary
Inferior hypophyseal arteries>capillary plexus of infundibular process> posterior hypophyseal veins>distribution to target cells
Oxytocin
Affects uterus and breasts. Allows for smooth muscle to contact during labor and for lactation for breast feeding.
Antidiuretic
Decreases urine production . Causes kidneys to return more water to the blood.
Fun fact: alcohol inhibits secretion of ADH.
Vasopressin
An antidiuretic which raises blood pressure
Osmoreceptors
Neurons in Hypothalamus that monitor blood osmotic pressure