Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Clin Med II Final > Endo Dx > Flashcards

Endo Dx Flashcards

0
Q

Low TSH

A

Hyper functioning thyroid

Lots of T3 to shut it down

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Best initial or screening test for thyroid function

A

TSH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

High TSH

A

Hypo functioning thyroid (no negative feedback from T3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

More direct measure of hormone activity

A

FREE T4

As opposed to total T4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Test to order if thinking Grave’s/hyperthyroid

A

Thyroglobulin (Tg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Monitoring tx of thyroid cancer and cancer recurrence

A

Thyroglobulin (Tg)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Thyroglobulin antibodies (TgAB)

Aka antithyroglobulin antibodies

A

Hashimoto’s disease (hypothyroid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Microsomal TPO antibodies

Aka antithyroid peroxidase ABs or antithyroid micrsomal ABs

A

Seen in 95% of Hashimoto’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Also seen in post partum thyroiditis

A

Microsomal TPO antibodies

Aka antithyroid peroxidase ABs or antithyroid micrsomal ABs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Positive ONLY in Hashimoto’s disease

A

TBab or TSBAb

Thyrotropin receptor blocking antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Prevent TSH from binding to the cell receptor

A

TBab or TSBAb

Thyrotropin receptor blocking antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

TSH receptor antibodies

Aka thyroid stimulating immunoglobulins (TSI)

A

Grave’s disease

Commonly seen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

After first screening TSH to determine if hypo or hyper thyroid

A

Check free T4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

If high TSH

A

Check T4 and all antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

If low TSH

A

Check free T4

And free T3, Tg, TPO antibodies, TgABs, TSI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Decrease blood calcium by suppressing bone resorption and inhibiting osteoclasts and inhibiting renal reabsorption of calcium

A

Calcitonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Distinguishes between solid vs cystic nodules

A

Thyroid ultrasound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Heterogenous nodules on ultrasound

A

Indicative of autoimmune destruction

Get thyroid fxn tests and repeat ultrasound in 6-12 mo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Nodules >4 mm

A

Biopsy

19
Q

Homogenous nodule

A

Benign, symmetrical

No need to repeat ultrasound

20
Q

Test of choice for dx the nature of thyroid nodules

A

Fine needle aspiration bx

21
Q

Follicular cells

A

Malignant until proven otherwise

22
Q

Used to differentiate btwn graves, toxic multi modular goiter, thyroiditis, malignancy

A

Thyroid nuclear medicine scan

23
Q

Hot thyroid gland on nuclear scan

A

Usually graves

24
Q

Nuclear scan: uptake low with patchy hot spots

A

Hashimoto’s thyroiditis

25
Q

Cold nodule

A

Probably cancer

26
Q

Still need bx to dx nodule

A

DO NOT BX HOT NODULE

Could send into thyroid storm

27
Q

If hot nodule but no clinical sx of graves

A

Rare but could be cancer

28
Q

Hormone that regulates ionized calcium minute to minute

A

Parathyroid hormone

29
Q

Hormone that stimulates intestinal calcium absorption

A

Calcitriol (vit D)

30
Q

Key to evaluation of of parathyroid disease

A

INTACT PTH

as opposed to total PTH

31
Q

Gold standard for evaluating and monitoring bone mineral density

A

DEXA

Dual energy X-ray absorptiometry

32
Q

Normal bone density on DEXA

A

T score >=. -1.0

33
Q

T score < -1.0 and > -2.5

A

Osteopenia

34
Q

T score < -2.5

A

Osteoporosis

35
Q

T score < -2.5 and prescience of one or more fragility fractures

A

Severe osteoporosis

36
Q

Valuable index of adrenal HYPERfunction

A

24 hour urinary free cortisol (17-OCHS)

Hyper adrenal function- cushings

37
Q

For evaluation of adrenal HYPOfunction

A

Cosyntropin stimulation test

Hypo adrenal function- Addison’s

38
Q

Evaluates ability of adrenal gland to respond to ACTH administration

A

Cosyntropin stimulation test

Positive response is >18 and >7 above baseline

39
Q

Evaluation of hypothalamic, pituitary AND adrenal fxn

A

Dexamethasone suppression test

40
Q

Decamethasone suppression test:

50% reduction of plasma cortisol and tribe 17- OCHS levels

A

Cushing’s disease (bilateral adrenal hyperplasia)

41
Q

Used in dx of pheochromocytoma

A

Clonidine suppression test

Must be done inpatient

42
Q

Mainstay for screening for intra-abdominal masses

A

CT scan

MRI more accurate but $$$$

43
Q

Excess prolactin

A

Galactorrhea
Gynecomastia
Hypo gonads
Amenorrhea

44
Q

Best way to eval GH excesses or deficiencies

A

IGF-1 better as screening tool

GH too many variations

Clin Med II Final (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions