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Renal > LM, IF. EM > Flashcards

LM, IF. EM Flashcards

1
Q
  • Normal-appearing glomeruli (early stages of the disease) or diffuse glomerular capillary wall thickening (later stages of the disease)
  • Silver stain → spike and dome pattern—the spikes are basement membrane material (colored black by the silver stain) and the domes are immune complex deposits (not colored by the silver stain).
A

Membranous nephropathy

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2
Q

Membranous nephropathy LM

A

(subepithelial) spike and dome pattern

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3
Q

Granular deposits of IgG and/or C3

A

Membranous nephropathy IF

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4
Q

Membranous nephropathy IF

A

Granular deposits of IgG and/or C3

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5
Q

Subepithelial (subpodocyte) immune complex deposits

A

Membranous nephropathy EM

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6
Q

EM membranous nephropathy

A

Subepithelial (subpodocyte) immune complex deposits

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Renal (22 decks)

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