Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Abx > Side effects > Flashcards

Side effects Flashcards

1
Q

TMP-SMX

A

Hyper K in renal injured patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Rifampin, isoniazid, pyrazinamide

A

Centrolobular hepatitis

*give B6/pyridoxine with isoniazid to prevent peripheral neuropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Rifampin

A

Flu-like hyper-sensitivity syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pyrazinamide

A

Gout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ethambutol

A

Optic neuritis, red/green color-blind

Blocks arabinosyl transferase (myco cell walls)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Acyclovir

A

Generally well-tolerated, except CNS if dosed inappropriately in renal patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ganciclovir

A

Neutropenia

Thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Foscarnet

A

Dose-dependent renal toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Oseltamivir

A

Neuropsychiatric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Zidovudine

A

Granulocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Lamivudine

A

Neutropenia
Pancreatitis
Rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Efavirenz

A

Rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Maraviroc

A

Susceptibility to microbes combatted by cell mediated immunity (TB, fungi)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Amprenavir

Ritonavir

A

Lipodystrophy syndrome: hyperglycemia, hyperlipidemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Fluroquinolones (-floxin)

A

Some 2nd gen: QT prolongation, torsades de pointes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Metronidazole

A

Disulfiram reaction (vasodilation and tachyarrhythmias)

17
Q

Gentamycin/Tobramycin

A

Nephrotoxic ONLY IF USED FOR LONG TIME

8th cranial nerve toxicity

Neuromuscular blockade

18
Q

Doxycycline

A

Photosensitivity

Chelates cations

19
Q

Azithromycin

A

GI distress

Torsades de pointes

20
Q

Linezolid

A

Agranulocytosis

21
Q

Clindamycin

A

Most associated with C. diff

22
Q

Lactams (penicillins, cephalosporins, carbapenem and monobactam)

A

Allergy: anaphylaxis, hives, angioedema

Maculpapular (lumpy/bumpy) skin rash
If from aminopenicillins, due to IgM, not IgE, not cross reactive with other penicillins

Penicillins and 1st gen ceph share cross-reactivity

Monobactams don’t cross-react with other lactams

People with penicillin allergies WON’T react to 2nd gen cephalosporins and higher

Ipipenem: seizures

23
Q

Vancomycin

A

Red man syndrome: flushing, tachycardia, hypotension if given too rapidly

24
Q

Daptomycin

A

Rhabdomyolysis

25
Q

Colistin

A

Nephrotoxic

26
Q

Imidazoles/clotrimazole

A

Too toxic for systemic use

27
Q

Triazoles

Allylamines

A

Systemic: rare hepatotoxcity

CYP inhibition leading to drug interactions

28
Q

Amphotericin B

A

Acute: fever, chills, hypotension during IV infusion

Chronic: Renal, Mg and P wasting, renal tubular acidosis, bone marrow suppression

29
Q

Flucytosine

A

GI mucosa sloughing, centrolobular hepatits, bone marrow cytopenia

Abx (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions