Cofactors Exam 2

Question 1

ATP ( Adenosine Triphosphate)

Answer 1

cosubstrate
Vita Source: none
transfer of phosphoryl or nucleotidyl groups

Question 2

NAD+ (Nicotinamide Adenine Dinucleotide)

Answer 2

cosubstrate
Vita Source: Niacin
oxidation-reduction involving two electron transfers

Question 3

FAD (Flavin Adenine Dinucleotide)

Answer 3

prosthetic group
Vita Source: Riboflavin
oxidation-reduction involving one and two electron transfers

Question 4

PLP (pyridoxal phosphate)

Answer 4

prosthetic group
Vita Source: Pyridoxine
transfer of groups to and from amino acids

Question 5

Coenzyme A

Answer 5

cosubstrate
Vita Source: Panthothenate
transfer of Acyl group “ A = Acyl”

Question 6

THF (tetrahydrofolate)

Answer 6

cosubstrate
Vita Source: Folate
Transfer of 1 carbon substituent, especially formyl or hydroxyl methyl groups; provides the methyl group for thymine in DNA

Question 7

Ubiquinone (Q)

Answer 7

cosubstrate
Vita Source: none
Lipid soluble electron carrier

Question 8

TPP ( Thiamine Pyrophosphate)

Answer 8

prosthetic group
Vita Source: Thiamine
Transfer of multi carbon fragments containing a carbonyl group

Question 9

Lipoamide

Answer 9

prosthetic group
Vita Source: none
Oxidation of hydroxyl alkl group from TPP and subsequent transfer as an acyl group

Question 10

Biotin

Answer 10

prosthetic group
Vita Source: Biotin
ATP dependent carboxylation of substrates or carboxyl group transfer between substrates