1b Neuromuscular Control Flashcards

(32 cards)

1
Q

what are alpha motor neurones?

A

The lower motor neurones of the brainstem and the spinal cord that innervate the extrafusal muscle fibres of skeletal muscles

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2
Q

What does activation of the alpha motor neurones cause?

A

Muscle contraction

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3
Q

What is a motor neurone pool?

A

Pool which contains all the alpha motor neurones which innervate a single muscle

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4
Q

what is a motor unit?

A

a single motor neuron together with all the muscle fibres that it innervates. It is the smallest functional unit with which to produce force.

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5
Q

What does stimulation of a motor unit cause?

A

Contraction of all the muscle fibres in that unit

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6
Q

What are Type 1 muscle fibres?

A

Slow - smallest cell bodies and smalled dendritic trees, thinnest axons and slowest conduction velocity

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7
Q

What are Type 2A muscle fibres?

A

Fast, fatiguable - larger diameter cell bodies, larger dendritic trees, thicker axons and faster conductions

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8
Q

What are Type 2B muscle fibres?

A

Fast, fatigue resistant - larger diameter cell bodies, larger dendritic trees, thicker axons and faster conductions

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9
Q

What are Type 2B muscle fibres?

A

Fast, fatiguable - larger diameter cell bodies, larger dendritic trees, thicker axons and faster conductions

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10
Q

Which type of muscle fibre produces the largest amount of force?

A

Type 2B

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11
Q

How are the three motor unit types classified?

A

amount of tension generated, speed of contraction and fatiguability.

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12
Q

What are the two mechanisms by which the brain regulates the amount of force a single muscle produced?

A

rate coding and recruitment

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13
Q

What is recruitment?

A

When smaller units are recruited first, and as more force is required, larger units are then recruited - this allows for fine control when necessary

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14
Q

What is rate coding?

A

When different units can fire at different frequencies - higher firing rate is larger force

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15
Q

When does summation occur?

A

When the muscle units fire at a frequency which is too fast to allow the muscle to relax between AP’s

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16
Q

what are neurotrophic factors?

A

a type of growth factors which prevent neuronal death and promote the growth of the neurones after injury

17
Q

What is the effect of neurotrophic factors?

A

If a fast twitch muscle and a slow muscle are cross innervated, the slow becomes fast and the fast becomes slow.

The motor neuron has some effect on the properties of the muscle fibres it innervates.

18
Q

What causes a change from IIB to IIA fibres?

19
Q

What causes a change from Type I to Type II?

A

Severe deconditioning or spinal cord injury, or microgravity

20
Q

What change is ageing associated with?

A

with loss of type I and II fibres but also preferential loss of type II fibres.

21
Q

What is the evidence that ageing results in a loss of type 1 and 2 fibres, with a preferential loss of type 2?

A

Larger proportion of type 1 fibres = slower contraction times

22
Q

What is a reflex?

A

An automatic response to a stimulus that involves a nerve impulse passing inward from a receptor to a nerve centre and then outward to an effector (as a muscle or gland) without reaching the level of consciousness.

23
Q

What is the Jendrassik Manoeuvre?

A

Try clenching the teeth, making a fist, or pulling against locked fingers when having patellar tendon tapped. The reflex becomes larger

24
Q

What type of control dominates in normal conditions?

A

Inhibitory control

25
What reveals the excitatory control from the supraspinal areas?
Decerebration
26
What can be the result of brain damage that causes an overactive or tonic stretch reflex?
Rigidity and spasticity
27
What is hyper-reflexia?
Overactive reflexes due to a loss of descending inhibition, and is associated with upper motor neuron lesions
28
What is Clonus (As a type of hyper-reflexia)?
Involuntary and rhythmic muscle contractions
29
What is the Babinski Sign?
When the sole of the foot is stimulated with a blunt instrument, the big toe curls upwards (in adults, this is abnormal)
30
When the sole of the foot is stimulated with a blunt object, what is the normal and pathological response in adult and kids?
Adults - Normal = Down, Pathological = Upwards Children - Normal = Upwards
31
What type of lesion is babinski sign associated with?
Upper motor lesions
32
What is hyporeflexia?
Below normal or absent reflex - associated with lower motor neurone disease