1st Exam Flashcards
(194 cards)
What are the four basic tissues of the human body?
epithelial, muscle, neural & connective tissues
What is osteology?
the study of bone
What are the three primary cell types of bone?
osteoblasts, osteocytes, and osteoclasts
What is the function of each type of bone cell?
osteoblast-form bone; osteocyte-maintain or nurture bone; osteoclast-remodel bone
What are the bone cells embedded in?
an amorphous matrix consisting of ground substance, protein fibers and various minerals
What is the primary constituent of the ground substance?
glycosaminoglycans
What types of glycosaminoglycans predominate in bone?
chondroitin sulfates, keratin sulfates, & hyaluronic acid
What is the principal type of protein fiber in bone?
collagen type I
What is the primary constituents of the bone mineral?
calcium, phosphate, citrate & carbonate ions
What is the most frequently described deposit in bone?
hydroxyapatite
Bone is also the repository for what additional ions?
sodium, magnesium, fluoride, lead, strontium, & radium
What is Wolff’s Law as it pertains to bone?
living tissue will respond to stressors; bone is formed or absorbed in response to stress
What are the three responses to bone that allow it to be described as “living”?
it has the ability to heal, to remodel under stressors and to age
What is bone the embryological derivative of?
mesenchyme or cartilage
What is the name given to the pattern of ossification in mesenchyme?
intramembranous ossification
What is the timing for the appearance of intramembranous ossification?
from the second to the third month in utero
What is the name given to the pattern of ossification in cartilage?
endochondral ossification
What is the timing for the appearance of endochondral ossification?
from the second to the fifth month in utero
What part of the skull is derived from endochondral ossification?
chondrocranium
Which bone of the appendicular skeleton is formed by both endochondral and intramembranous ossification?
the clavicle
What are the names given to the centers of ossification based on time of appearance?
primary centers of ossification appear before birth
secondary centers of ossification appear after birth
Mature bone is described as being composed of what areas based on bone density?
cortical or compound bone and spongy, cancellous or trabecular bone
What is the name given to a bone BELOW an articulating surface?
subchondral bone
What is the name of the outer fibro-cellular COVERING of bone?
the periosteum