1st Partial Flashcards

(50 cards)

1
Q

What are crosslinks in the context of aging?

A

CONNECTIONS BETWEEN PROTEINS IN TISSUES

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2
Q

How does a scarcity of nutrients impact cellular function?

A

IT BOOSTS CELLULAR REPAIR AND MAINTENANCE MECHANISMS

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3
Q

What is the primary indicator of a country transitioning Stage 4 of the Demographic Transition Model?

A

DECREASING DEATH RATES

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4
Q

What is cellular senescence?

A

PROCESS OF CESSATION OF CELL DIVISION

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5
Q

Which stage of the Demographic Transition Model is characterized by rapid population growth over low death rates and high birth rates?

A

STAGE 2 (EARLY EXPANDING)

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6
Q

Which type of diseases has shown a growing impact with increasing longevity?

A

CHRONIC AND NONCOMMUNICABLE DISEASES

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7
Q

What does the width of the base of an expansive population pyramid indicate?

A

HIGH BIRTH RATES

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8
Q

What term refers to the portion of our lives during which we are free of disease?

A

HEALTH EXPECTANCY

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9
Q

With respect to AGING, select the WRONG statement:

A

THE CHANGES IN THE LIVING BEING, THROUGH THE YEARS, PRODUCE AN INCREASE IN THE ADAPTABILITY CAPACITY OF THE ORGANISM IN RELATION TO THE ENVIRONMENT

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10
Q

What is the Hayflick Limit?

A

A LIMIT ON CELLULAR REPLICATION

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11
Q

What is the primary goal of addressing aging in the medical community?

A

TO OPTIMIZE HEALTH EXPECTANCY

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12
Q

What are free radicals, and how do they contribute to mitochondrial damage?

A

HARMFUL SUBSTANCES PRODUCED DURING MITOCHONDRIAL FUNCTION

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13
Q

What is inflammaging?

A

A STATE OF CONTINUOUS INFLAMMATION IN AGING-RELATED DISEASES

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14
Q

Which pharmacological agent, commonly prescribed for arterial hypertension, is associated with a notable side effect of gingival enlargement?

A

CALCIUM CHANNEL BLOCKERS

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15
Q

What is the primary goal of senolytics?

A

TO TARGET AND REMOVE SENESCENT CELLS

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16
Q

What does the term ‘demographic transition’ refer to?

A

THE PROCESS OF MOVING FROM HIGH BIRTH AND DEATH RATES TO LOW BIRTH AND DEATH RATES OVER TIME

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17
Q

What are telomeres?

A

PROTECTIVE REGIONS AT THE END OF CHROMOSOMES

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18
Q

How does protein homeostasis contribute to cellular function?

A

BY PROMOTING PROTEIN BREAKDOWN AND RECYCLING

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19
Q

What type of population pyramid is shown in the image? (uniforme)

A

STATIONARY PYRAMID

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20
Q

What is a population pyramid?

A

A GRAPHICAL REPRESENTATION OF THE AGE AND SEX DISTRIBUTION OF A POPULATION

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21
Q

What role does the immune system play in clearing senescent cells?

A

IT ELIMINATES SENESCENT CELLS

22
Q

What led to the implementation of the General Population Law in Mexico in 1974?

A

HIGH FERTILITY RATES

23
Q

What is the main determinant of population aging?

A

DECREASING FERTILITY RATES

24
Q

What type of population pyramid is shown in the image? (bajo-crece-bajo)

A

CONSTRICTIVE PYRAMID

25
Force exerted against the arterial wall by blood flowing through arteries
BLOOD PRESSURE
26
What happens when telomeres become critically short?
THEY CANNOT PROTECT DNA ANYMORE, LEADING TO DAMAGE
27
Which demographic trend is associated with a transition from an expansive to a constrictive population pyramid?
DECREASING BIRTH RATES AND INCREASING LIFE EXPECTANCY
28
What are the consequences of not clearing senescent cells?
INCREASED INFLAMMATION
29
What is the primary function of stem cells in the body?
TISSUE REPAIR AND REGENERATION
30
What type of country is typically associated with a constrictive population pyramid?
DEVELOPED COUNTRIES WITH LOW BIRTH AND DEATH RATES
31
What is a significant factor contributing to the decrease in fertility rates?
INCREASED ACCESS TO EFFECTIVE BIRTH CONTROL
32
What additional information can be extrapolated from a population pyramid?
ALL OF THE ABOVE (ECONOMIC DEVELOPMENT, MIGRATION PATTERNS, HISTORICAL EVENTS)
33
What is the primary mechanism through which a low-sugar diet slows down aging?
BY REDUCING THE FORMATION OF CROSSLINKS
34
How does consuming foods high in sugars contribute to aging?
IT ACCELERATES THE FORMATION OF CROSSLINKS
35
Why is cellular senescence considered a protective mechanism?
IT PREVENTS THE DEVELOPMENT OF CANCER
36
Which of the following symptoms may indicate advanced arterial hypertension?
ALL OF THE ABOVE (NAUSEA OR VOMITING, OCCIPITAL HEADACHE, SHORTNESS OF BREATH)
37
Stem cell exhaustion contributes to an increase in regenerative capacity over time
FALSO
38
What process is responsible for clearing damaged mitochondria from cells?
MITOPHAGY
39
What is the consequence of protein accumulation inside cells?
CELLULAR DYSFUNCTION
40
How does the shape of a population pyramid change as a population ages?
IT BECOMES WIDER AT THE TOP
41
What are some characteristics of aging?
HETEROGENEITY AND SINGULARITY
42
Primary hypertension primarily stems from various etiologies, yet which factor is not typically associated with its development?
ENDOCRINE DISEASES
43
How does protein accumulation affect blood vessels?
IT MAKES THEM MORE FRAGILE
44
What has led to the shift in the causes of death from infectious diseases to chronic conditions
IMPROVEMENTS IN MEDICAL TECHNOLOGIES
45
In which type of country is an expansive population pyramid typically found?
DEVELOPING COUNTRIES WITH HIGH BIRTH AND DEATH RATES
46
Which aging disease is associated with protein accumulation in the brain?
ALZHEIMER’S DISEASE
47
How is aging defined?
A PROGRESSIVE PHYSIOLOGICAL PROCESS OCCURRING FROM CONCEPTION ONWARDS
48
What does a stationary population pyramid indicate?
STABLE BIRTH AND DEATH RATES
49
What happens when mitochondria evade destruction through mitophagy?
THEY ACCUMULATE IN CELLS
50
Which stage of the Demographic Transition Model is characterized by high birth and death rates, resulting in minimal population growth?
STAGE 1 (HIGH STATIONARY)