1st Trimester Flashcards

(74 cards)

1
Q

When does conceptual/embryologic age begin?

A

With the first day of conception, after ovulation

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2
Q

When does gestational age begin? Is this earlier or later than conceptional age.

A

With the first day of the LMP. It’s about 2 weeks before the conceptual age.

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3
Q

At what point is a zygote created? When does it become an embryo? When is it a fetus?

A

A zygote is from conception to 12 days. An embryo is from implantation to the end of the 10th week. A fetus is from 10 weeks to birth.

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4
Q

What is a morula? What is a blastocyst?

A

When a zygote undergoes cellular division and becomes 16 cells it is a morula. When it becomes 32 cells it is a blastocyst.

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5
Q

What happens to the follicle that released the ovum?

A

It collapses to form the corpus luteum and secretes estrogen and progesterone.

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6
Q

The blastocyst enters the uterus and attaches to the wall about 4 days after fertilization. What do the parts of a blastocyst do?

A

The ring of trophoblastic cells secrete HCG and the inner cell mass begins to form the embryo.

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7
Q

Implantation is typically completed within 12 days of fertilization. What occurs during this stage?

A

enzymes from the trophoblasts “eat into the maternal tissue and are nourished with lacunae: blood pools from capillaries. The zygote buries itself into the wall.

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8
Q

What is the difference between primary and secondary yolk sacs?

A

The cell mass becomes the primary yolk sac. 23 days after fertilization, the primary is pinched off and becomes the secondary yolk sac, which is seen throughout the first trimester.

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9
Q

What is the first system to develop? When can you tell?

A

The cardiovascular system develops the fastest. The heartbeat is visible around 5 or 6 weeks.

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10
Q

About how much does HCG level change every few days in a normal intra uterine pregnancy?

A

For the first 7 weeks, it doubles every 3 or 4 days. At 9-10 weeks HCG plateaus and then gradually declines.

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11
Q

High or Low HCG can indicate what types of abnormalities?

A

high HCG could indicate Down Syndrome whereas Low HCG can indicate ectopic pregnancies

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12
Q

What are the strongest biochemical markers for down syndrome?

A

PAPP-A analysis at 9-11 weeks combined with HCG levels.

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13
Q

What is a yolk sac and what is its purpose?

A

The earliest intragestational sac seen around 5 weeks. It provides nutrients to the embryo before the placenta forms.

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14
Q

The yolk sac should be visualized when the gestational sac measures ___ mm? The embryo should be seen when it measures __mm?

A

The mean sac diameter should be >12mm to visualize the yolk sac and >18mm to see the embryo.

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15
Q

Does visualization of the yolk sac always predict viable pregnancy?

A

Not always but at least in 90% of cases

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16
Q

The number of amnion membranes is consistent with the number of ________ in twin pregnancies.

A

yolk sacs.

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17
Q

What happens at the beginning of week 5 when the bilaminar embryonic disk turns into the trilaminar disk?

A

organogenesis can begin.

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18
Q

What must be visualized when the CRL >4mm in order to declare a living embryo?

A

Heart motion

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19
Q

When does chorioamniotic fusion of membranes occur?

A

14-15 weeks.

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20
Q

Where does the spine develop from? At what week is the spine visalized as parallel echogenic lines?

A

It develops from the ectoderm and is visible at around 6 weeks

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21
Q

What are the segments called when the rhombencephalon divides in two?

A

The cephalic portion is the metencephalon and the caudal component is the myelencephalon

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22
Q

Once rhombencephalon divides, cystic rhomboid fossa forms. What week can this be imaged?

A

From 8 to 10 weeks

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23
Q

Limb buds are embryonically recognizable at what week of gestation?

A

6th

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24
Q

Which limbs develop first?

A

upper limbs

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25
When does the midgut finally descend into the abdomen
week 11
26
When is the umbilical cord no longer visualized and the bowel is able to be seen on ultrasound?
after 12 weeks gestation
27
what is the first organ to function in the embryo
the heart
28
At what point is a fetal heartrate considered bradycardia
less than 90 bpm
29
At what point is a fetal heartrate considered tachycardia
over 160 bpm
30
What are the two parameters for sonographic gestational dating? When would you use each?
CRL if visible and MSD if CRL cannot be seen
31
how do you calculate MSD?
mean sac diameter = (Length + width + height) / 3
32
How do you calculate Menstrual age?
MSD + 30
33
How long is CRL the most accurate measurement for dating? Why?
through 12 weeks gestation. After this, the fetus curls up and becomes difficult to measure.
34
Why do we use a TV probe with first trimester pregnancies
it allows us to see small structures like the embryo and yolk sac sooner.
35
What is the earliest structure seen within a gestational sac? What does this indicate?
A yolk sac indicates true intrauterine pregnancy
36
When examining the ovaries, what should you be sure to document?
Their texture and presence of corpus luteum.
37
what percent of clinically recognized pregnancies result in miscarriage
about 15%
38
what percent of pregnancies present with 1st trimester bleeding?
about 25%
39
is a pregnancy with bleeding viable
often times yes.
40
is a pregnancy with severe pain and dilated cervix likely to progress?
no
41
What happens with a detached placenta?
Formation of hematoma leading to and 50% fetal loss rate
42
What is the most common occurence of 1st trimester bleeding?
subchorionic hemorrhage
43
What are possible causes of a positive pregnancy test and an empty uterus
too early to see G sac, non-developing pregnancy, ectopic
44
Approximately how much do both the embryo and yolk sac grow each day in the 1st trimester
1 mm / day
45
How large should the gestational sac be when the yolk sac is visualized?
8 mm
46
What should the mean sac diameter be when the embryo is visualized?
MSD of at least 16 mm
47
At what embryonic length OR sac diameter can pregnancy loss be determined?
The embryo should be 7mm or greater without a heartbeat OR the MSD is 25mm without visible embryo.
48
What is a threatened abortion
bleeding patient with closed Cx but living fetal pole
49
What is an incomplete abortion
Some products passed but some remain
50
What is a complete abortion
empty uterus since all products passed
51
What is a missed abortion
non-viable fetus without heartbeat
52
What is an inevitable abortion
dilated Cx with fluid, subchorionic hemorrhage surrounding sac
53
What is a septic abortion
infection with increased vascularity due to retained products.
54
What are sono signs of retained products?
high vascularity and thickened endometrium
55
What is an anembryonic pregnancy also called
blighted ovum
56
what is an anembryonic pregnancy?
A growing gestational sac without embryo or yolk sac.
57
What is Gestational Trophoblastic Disease? What are the 3 types
Proliferative disease of trophoblast where non-viable mass forms in uterus instead of embryo
58
Describe a complete mole in Gestational Trophoblastic Disease
No viable embryonic tissue or sac.
59
Describe a partial mole in Gestational Trophoblastic Disease
molar and IUP
60
Describe a invasive mole in Gestational Trophoblastic Disease
through myometrium and can extend outside of uterus
61
What pathology and appearance are associated with gestational trophoblastic disease
Theca Lutein cysts in ovaries and the snowstorm appearance.
62
What is another term for gestational trophoblastic disease?
Hydatidiform
63
What is choriocarcinoma?
malignant form of trophoblastic with fast growing tumor that can metastassize to lungs, liver, brain
64
10% of maternal deaths are linked to what pathology? Where do most of these occur?
ectopic pregnancy. 95% are in fallopian tube
65
What happens with an interstitial/cornual pregnancy?
the pregnancy occurs at the cornua which is very vascular. when the pregnancy ruptures, it creates a life threatening hemorrhage
66
Which type of ectopic pregnancy might cause histerectomy? why?
cervical because of the uncontrollable bleeding caused by the vascularity of the cervix.
67
What is decidua basalis?
deepst layer around the maternal side of implantation site.
68
What is decidua capsularis?
the thin part of the endometrium that forms around the capusle
69
What is decidua paratalis?
the part of the endometrium that is not occupied by implantation
70
what are chorionic villi
the projections of the placenta that extend into the endo
71
what are chorion frondosum
the projections of the chorion that extend into the decidua basalis
72
What is nuchal translucency
it measures the fluid at the posterior neck for trisomy around 11-13 weeks
73
What are symptoms of molar pregnancy
high HCG, hyperemesis, bleeding
74
What pathology is associated with the umbilical cord? Can this pregnancy still be viable?
umbilical cord cysts. they often resolve in the 2nd trimester