Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Farm > 2 > Flashcards

2 Flashcards

1
Q

What is the halftime for esmolol due to?

A

Hydrolysis 

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the onset and duration of esmolol?

A

 Onset is 5 minutes
Duration is 10 to 30 minutes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are two reasons you would not give esmolol?

A

AV heart block
Heart failure not caused by tachycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is a selective Beta 1 antagonist with rapid onset?

A

Esmolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the dose of esmolol?

A

 0.5 Mg/kg over 60 seconds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What can be given two minutes before DL and how much? Why?

A

150 mg of Esmolol
Provides protection against increase in heart rate and SBP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What two things can happen from a large IV bolus of precedex?

A

Bradycardia
Paradoxial hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What medication does precedex resemble in a large IV boluses? Why?

A

Phenylephrine
Due to cross over alpha-1 stimulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What drug has a 1600 to 1 affinity for alpha-2 receptors compared to alpha-1 receptors?

A

Dexmedetomidine (Precedex)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What receptors do phentolamine and phenoxybenzamine work on?

A

Post synaptic alpha-1
Presynaptic alpha-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the normal dose of phenoxybenzamine?

A

0.5 - 1mg PO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the drug of choice for prehospital management for pheochromocytoma?

A

Phenoxybenzamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Protein binding from greatest to least for beta blockers?

A

Propanolol > metoprolol > atenolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What three things do you see with Beta 1 receptor blockades

A

Slow sinus rate
Slows conduction of cardiac impulses through the AV node
Decreases inotrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

A person taking beta, adrengeric blockade medication, experiences life-threatening bradycardia and hypotension. What would you treat this overdose with?

A

Glucagon because it increases cAMP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are three side effects caused by labetalol?

A

Orthostatic hypotension (most common)
Bronchospasm
Fluid retention from prolonged therapy (use diuretics)

17
Q

What are two things regarding a labetalol therapy?

A

Selective alpha 1 antagonist
Direct vasodilation

18
Q

What medication should be avoided in asthmatics?

A

Labetalol

19
Q

What two things does the initiation of labetalol cause?

A

Decrease in SVR by alpha-1 blockade
Attenuates tachycardia by Beta blockade

20
Q

What is not a Pharmalogical response from labetalol?

A

Release of catecholamines

21
Q

What type of medication is isoproterenol?

A

Beta 1 agonist.
It is not a beta blocker.

22
Q

What has the most potent beta 1 and beta 2 effects?

A

Isoproterenol

23
Q

What beta blocker does not interact with digoxin?

A

Clonidine

24
Q

What medication do calcium channel blockers increase the concentration of?

A

Digoxin

25
Q

A patient with pre-existing, cardiac conduction abnormalities may have a greater degree of AV heart block when given what two drugs?

A

Verapamil
Digoxin

26
Q

What is the pathway that refers to processing of fats cholesterol and vitamins?

A

Exogenous

27
Q

What is the pathway that describes hepatic cholesterol synthesis and its distribution to tissue?

A

Endogenous

28
Q

What two drugs should be used with caution when giving a patient calcium channel blockers, like dantrolene?

A

Verapamil
Diltiazem

29
Q

What are two things that verapamil can cause?

A

Negative Chronotropic affects
Moderate vasodilation

30
Q

Verapamil has what kind of affects on inotrophy?

A

Negative

31
Q

What does verapamil do to coronary and systemic arteries?

A

Vasodilation

32
Q

What effects does the dextroisomer of verapamil have at slow calcium channels?

A

It’s devoid meaning no activity

33
Q

How does the dextroisomer of verapamil at on sodium channels?

A

Acts on fast sodium channels, accounting for local anesthesia effects

34
Q

Lidocaine, diazepam, and propanolol can increase the pharmacologically, active, unbound portion of which drug?

A

Verapamil

35
Q

What medication would you not give for an acute myocardial ischemia?

A

Verapamil

36
Q

True or false: Epi is a direct general agonist

A

True

37
Q

What medication increases conduction velocity and decreases refractory period?

A

Epi

38
Q

True or false: phenylephrine is purely alpha?

A

True

Farm (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions