2. Dermatology Flashcards Preview

ESA 4- Integrative > 2. Dermatology > Flashcards

Flashcards in 2. Dermatology Deck (7)
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1

Name 6 functions of the skin.

1. Protective barrier against environmental insults, inc. trauma, UV light and pathogens

2. Immunosurveillance

3. Sensation

4. Temperature and fluid regulation

5. VitD synthesis

6. Cosmesis

2

Label.

3

Name the 4 major cell types of the epidermis and state their function.

1. Keratinocytes - protective barrier

2. Langerhans cells (stratum spinosum) - APCs

3. Melanocytes (stratum basale) - melanin protection to protect nuclei from UV DNA damage

4. Merkel cells - mechanoR cells for sensation 

4

Describe the 4 layers of the epidermis. Where is an extra layer found?

1. Stratum corneum

2. Stratum granulosum

3. Stratum spinosum

4. Stratum basale - site of keratinocyte mitosis. Cells then move up layers, losing ability to divide.

 

Stratum lucidum found in areas of thicker skin, e.g. palms and soles.

5

What is the dermis composed of?

Collagen, elastin and glycosaminoglycans - provides strength and elasticity.

 

Also contains immune cells, nerve cells, skin appendages. lymphatics and blood vessels. 

6

What is this condition? Why can it occur and what are the symptoms and consequences?

ERYTHRODERMA = general exfoliative dermatitis with erythema and scaling, involving 90%+ of P's skin

 

Most commonly caused by exacerbation of underlying skin condition, e.g. psoriasis or eczema, but can also be caused by drug allergy or cutaneous T cell lymphoma.

 

Symptoms: pruritis, fatigue, anorexia, cold

 

Complications:

- hypothermia (loss of thermoregulation)

- infection (loss of protective barrier)

- renal failure (insensible losses)

- cardiac failure (dilated skin vessels)

- protein malnutrition (high skin turnover)

7