2(E): Hypoglycaemia Flashcards

1
Q

What is the commonest endocrine emergency

A

Hypoglycaemia

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2
Q

What defines hypoglycaemia

A

<3mmol/L

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3
Q

What is the most common cause of hypoglycaemia in diabetics

A

Over-use of insulin and sulphonylureas

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4
Q

What is mnemonic to remember cause of hypoglycaemia in non-diabetics

A

EXPLAIN

EXogenous medications 
Pituitary insufficiency 
Liver failure 
Addison's disease
Islet cell tumour (Insulinoma) 
Non-pancreatic neoplasms
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5
Q

What exogenous drugs can cause hypoglycaemia

A
  • B-blocker
  • Alcohol
  • Aspirin poisoning
  • ACEi
  • Quinine
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6
Q

What non-pancreatic neoplasm can cause hypoglycaemia

A

Fibrosarcoma

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7
Q

When may post-prandial hypoglycaemia occur

A

Following bariatric surgery

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8
Q

When do symptoms of hypoglycaemia usually onset

A

Glucose <2.6mmol/L

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9
Q

What are the autonomic symptoms of hypoglycaemia

A

Increase sympathetic activity:

  • Tachycardia
  • Sweating
  • Pallour
  • Anxiety
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10
Q

What are neuroglycopenic symptoms

A
  • Agitation
  • Confusion
  • Behavioural change
  • Seizures
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11
Q

What is first line investigation for hypoglycaemia

A

Capillary blood glucose

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12
Q

When should non-diabetics be investigated for hypoglycaemia

A
  • Signs and Symptoms of low glucose
  • Low plasma glucose
  • Resolution of symptoms following glucose rise
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13
Q

What may be ordered in hypoglycaemia

A

Lab Glucose
Insulin
C-Peptide

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14
Q

How is hypoglycaemia managed if conscious

A

If conscious and able to swallow give 15-20g of carbohydrate snack and measure blood glucose in 15m

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15
Q

How is hypoglycaemia managed if patient is conscious but not co-operative

A

Glucogel

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16
Q

How is hypoglycaemia managed if unconscious

A

10% Dextrose IVI or glucagon IM/IV

17
Q

What is problem with glucagon for hypoglycaemia

A

will not work in malnourished patients